Cancer Tissue Gallery DOG-1

Breast – Carcinoma of no special type (NST) showing moderate to strong membranous DOG1 positivity.

Breast – DOG1 negative invasive lobular carcinoma. DOG1 immunostaining is seen in the basal cell layer of an excretory duct.

Colon – Colorectal adenocarcinoma showing a moderate DOG1 staining, predominantly at the apical membranes of cancer glands.

Colon – Colorectal adenocarcinoma showing DOG1 negative tumor cells but moderate focal DOG1 stroma staining.

Colon – Colorectal adenocarcinoma with strong membranous DOG1 positivity.

Esophagus – Adenocarcinoma showing strong membranous DOG1 immunostaining.

Esophagus – Moderate to strong membranous DOG1 immunostaining in an esophageal adenocarcinoma.

Liver – Cholangiocellular carcinoma with DOG1 negative tumor cells but weak to moderate DOG1 stroma staining.

Lung – Pulmonary adenocarcinoma showing moderate to strong membranous DOG1 immunostaining.

Oral cavity – Squamous cell carcinoma with weak to moderate DOG1 immunostaining in basal cell layers.

Ovary – Mucinous carcinoma with a moderate DOG1 staining at the apical membranes of dilatated cancer glands.

Pancreas – Adenocarcinoma of the papilla Vaterii pancreas with DOG1 negative tumor cells but strong focal DOG1 stroma staining.

Pancreas – DOG1 negative ductal adenocarcinoma.

Pancreas – Ductal adenocarcinoma of the pancreas with focal moderate to strong membranous DOG1 immunostaining.

Pancreas – Ductal adenocarcinoma of the pancreas with moderate to strong membranous DOG1 positivity in all tumor cells.

Pancreas – Ductal adenocarcinoma with strong membranous DOG1 immunostaining.

Pancreas – Ductal adenocarcinoma with strong membranous DOG1 immunostaining.

Pancreas – Neuroendocrine tumor showing DOG1 negative tumor cells but weak to moderate DOG1 stroma staining.

Stomach – Gastric adenocarcinoma with a moderate to strong membranous DOG1 staining.

Stomach – Gastric adenocarcinoma with a weak a moderate DOG1 staining, predominantly at the apical membranes of cancer glands.

Urinary bladder – Muscle-invasive urothelial carcinoma showing a strong membranous DOG1 positivity.

Uterus – Endometroid endometrium carcinoma showing a moderate DOG1 staining, predominantly at the apical membranes of cancer glands.

Uterus – Endometroid endometrium carcinoma with a moderate DOG1 staining at the apical membranes of cancer glands.

Uterus – DOG1 negative endometroid endometrium carcinoma with weak DOG1 staining of the tumor stroma.

Vulva – Squamous cell carcinoma with moderate DOG1 immunostaining in basal cell layers.

Vulva – Squamous cell carcinoma with moderate to strong DOG1 immunostaining, predominantly in basal cell layers.

Vulva – Squamous cell carcinoma with strong DOG1 immunostaining, limited to basal cell layers.