Cancer Tissue Gallery Melan A+

Adrenal gland – Adrenocortical adenoma showing diffuse strong Melan A+ positivity.

Adrenal gland – Adrenocortical carcinoma with diffuse Melan A+ positivity of all tumor cells.

Breast – Breast cancer of no special type showing diffuse weak Melan A+ immunostaining.

Colon – Melan A+ negative colorectal adenocarcinoma.

Kidney – Angiomyolipoma with a strong diffuse Melan A+ immunostaining.

Kidney – Angiomyolipoma with a weak to moderate Melan A+ immunostaining also involving fat cells.

Kidney – Angiomyolipoma with a weak to moderate Melan A+ positivity.

Kidney – Oncocytoma with moderate Melan A+ immunostaining of tumor cells.

Pancreas – Melan A+ negative ductal adenocarcinoma.

Pharynx – Squamous cell carcinoma showing diffuse weak Melan A+ immunostaining.

Prostate – Melan A+ negative prostatic adenocarcinoma (Gleason 3+3=6).

Skin – Malignant melanoma displaying only a very faint (equivocal) Melan A+ immunostaining in about 50% of tumor cells.

Skin – Malignant melanoma showing diffuse strong Melan A+ positivity.

Skin – Malignant melanoma showing Melan A+ immunostaining of variable intensity in tumor cells (mosaic pattern).

Skin – Malignant melanoma with strong Melan A+ positivity in all tumor cells.

Skin – Melan A+ negative basal cell carcinoma containing numerous (non-neoplastic) melanocytes.

Skin – Melan A+ negative squamous cell carcinoma.

Urinary bladder – Muscle-invasive urinary bladder cancer showing weak to moderate Melan A+ immunostaining.

Urinary bladder – Muscle-invasive urinary bladder cancer with focal weak Melan A+ positivity.