Cancer Tissue Gallery Cadherin-16 / CDH16

Adrenal gland – CDH16 negative adrenocortical adenoma.

Esophagus – CDH16 negative adenocarcinoma.

Kidney – Chromophobe renal cell carcinoma with strong CDH16 immunostaining of tumor cells (CDH16 immunohistochemistry)

Kidney – Clear cell renal cell carcinoma with weak to moderate CDH16 staining of a fraction of tumor cells (CDH16 immunohistochemistry).

Kidney – Oncocytoma with strong CDH16 immunostaining of tumor cells (CDH16 immunohistochemistry).

Kidney – Papillary renal cell carcinoma with weak CDH16 staining of most tumor cells (CDH16 immunohistochemistry).

Liver – CDH16 negative hepatocellular carcinoma.

Lung – CDH16 negative adenocarcinoma.

Lung – CDH16 negative small cell carcinoma.

Lung – CDH16 negative squamous cell carcinoma.

Lung – Neuroendocrine tumor showing strong CDH16 staining of tumor cells (CDH16 immunohistochemistry).

Lymph node – CDH16 negative Hodgkin’s lymphoma.

Oral cavity – CDH16 negative squamous cell carcinoma.

Ovary – CDH16 negative serous high-grade carcinoma.

Ovary – Clear cell carcinoma with strong CDH16 immunostaining of tumor cells (CDH16 immunohistochemistry).

Ovary – Endometroid carcinoma with strong CDH16 immunostaining of tumor cells (CDH16 immunohistochemistry).

Pancreas – CDH16 negative neuroendocrine tumor.

Pancreas – Neuroendocrine tumor with moderate to strong CDH16 positivity of tumor cells (CDH16 immunohistochemistry)

Prostate – CDH16 negative adenocarcinoma (Gleason 3+3=6)

Salivary gland – CDH16 negative Warthin tumor.

Soft tissue – CDH16 negative leiomyosarcoma.

Soft tissue – CDH16 negative liposarcoma.

Stomach – CDH16 negative adenocarcinoma.

Stomach – CDH16 negative gastrointestinal stromal tumor (GIST).

Testis – CDH16 negative seminoma

Thyroid – CDH16 negative medullary carcinoma.

Thyroid – CDH16 negative papillary carcinoma invading CDH16 positive normal thyroid (CDH16 immunohistochemistry)

Thyroid – CDH16 staining is lacking in a papillary thyroid carcinoma but clearly visible in adjacent normal thyroid (CDH16 immunohistochemistry).

Thyroid – Complete lack of CDH16 staining in a follicular carcinoma (CDH16 immunohistochemistry)

Thyroid – Complete lack of CDH16 staining in a papillary carcinoma (CDH16 immunohistochemistry).

Thyroid – Follicular adenoma with strong CDH16 immunostaining of tumor cells (CDH16 immunohistochemistry).

Urinary bladder – CDH16 negative muscle-invasive urothelial carcinoma.

Uterus – Endometroid endometrium carcinoma with weak to moderate CDH16 immunostaining of the majority of tumor cells (CDH16 immunohistochemistry).

Uterus, cervix – Adenocarcinoma with strong CDH16 staining in about 60_ of tumor cells (CDH16 immunohistochemistry).