Normal Tissue Gallery Nucleolin

Adrenal gland

Aorta, media

Appendix, mucosa

Appendix, muscular wall – The entire nuclei of smooth muscle cells are nucleolin positive but the immunostaining is most distinct in the nucleolus.

Bone marrow

Breast

Bronchus, mucosa – In the respiratory epithelium, nucleolin staining is more prominent in basal and goblet cells than in the ciliated cells. The focus of the immunostaining to the nucleoli becomes most visible in the less stained ciliated cells, however.

Cerebellum (molecular layer, Purkinje cell layer, granule cell layer, white matter)

Cerebellum (molecular, Purkinje cell, granule cell layers; white matter)

Cerebrum, grey matter

Cerebrum, white matter

Colon descendens, mucosa – In the colon, nucleolin staining is more prominent in the proliferating cells in the crypt base than in the less proliferative superficial cell layers. The focus of the immunostaining to the nucleoli becomes most visible in the less stained superficial cells, however.

Colon descendens, muscular wall

Duodenum, Brunner gland

Duodenum, mucosa

Epididymis

Esophagus, squamous epithelium -The entire nuclei of epithelial cells are positive but the nucleolin immunostaining is often most distinct in the nucleoli.

Fallopian tube, mucosa – The entire nuclei of epithelial cells are nucleolin positive but the immunostaining is most distinct in the nucleoli.

Fat

Gallbladder, epithelium – The entire nuclei of epithelial cells are nucleolin positive but the immunostaining is most distinct in the nucleoli.

Heart muscle

Ileum, mucosa

Kidney, cortex

Kidney, medulla

Liver

Lung

Lymph node

Ovary, stroma

Pancreas

Parathyroid

Parotid gland

Pituitary gland, anterior lobe

Pituitary gland, posterior lobe

Placenta (amnion) – The entire nuclei of amnion cells are positive but the nucleolin immunostaining is often most prominent in the nucleoli.

Placenta (chorion)

Placenta, early

Placenta, mature

Prostate

Rectum, mucosa – In the rectum, nucleolin staining is more prominent in the proliferating cells in the crypt base than in the less proliferative superficial cell layers. The focus of the immunostaining to the nucleoli becomes most visible in the less stained superficial cells, however.

Seminal vesicle

Sinus paranasales – In this sample of respiratory epithelium, nucleolin staining is particularly prominent in the nucleoli of epithelial (and also inflammatory) cells.

Skeletal muscle

Skin

Spleen

Stomach, antrum – In the gastric mucosa, nucleolin staining is more prominent in the proliferating neck cells than in the less proliferative glands. The focus of the immunostaining to the nucleoli becomes most visible in the glands, however.

Stomach, corpus

Testis

Thymus

Thyroid gland

Tonsil, surface epithelium – In the surface epithelium, nucleolin staining is more prominent in the basal and suprabasal cells than in the superficial cell layers. The entire nuclei of epithelial cells are positive but the nucleolin immunostaining is often most distinct in the nucleoli.

Tonsil

Urinary bladder, muscular wall – The entire nuclei of smooth muscle cells are nucleolin positive but the immunostaining is most distinct in the nucleoli.

Urinary bladder, urothelium – Nucleolin immunostaining is most prominent in the nucleoli of urothelial cells.

Uterus, ectocervix

Uterus, endocervix

Uterus, endometrium (pregnancy)

Uterus, endometrium (proliferation) – Strong diffuse nucleolin immunostaining of the entire nuclei in all cells.

Uterus, endometrium (secretion) – In this sample of endometrium, nucleolin staining is particularly prominent in the nucleoli of epithelial (and also inflammatory) cells.

Uterus, myometrium