Adrenal gland
Adrenal glandAnal canal, skin – A weak to moderate, mostly membranous MUC1 immunostaining is seen in this keratinizing squamous epithelium from the anal skin.
Anal canal, skin - A weak to moderate, mostly membranous MUC1 immunostaining is seen in this keratinizing squamous epithelium from the anal skin. Aorta, media
Aorta, mediaAppendix, mucosa
Appendix, mucosaAppendix, muscular wall
Appendix, muscular wallBone marrow
Bone marrowBreast – A moderate to strong cytoplasmic MUC1 immunostaining with apical predominance is seen in breast glands. MUC1 staining may be weaker in basal cells.
Breast - A moderate to strong cytoplasmic MUC1 immunostaining with apical predominance is seen in breast glands. MUC1 staining may be weaker in basal cells. Bronchus, mucosa – A variable, moderate to strong MUC1 staining occurs in respiratory epithelium.
Bronchus, mucosa - A variable, moderate to strong MUC1 staining occurs in respiratory epithelium. Bronchus, mucosa – A variable, moderate to strong MUC1 staining occurs in respiratory epithelium.
Bronchus, mucosa - A variable, moderate to strong MUC1 staining occurs in respiratory epithelium. Cerebellum (molecular layer, Purkinje cell layer, granule cell layer, white matter)
Cerebellum (molecular layer, Purkinje cell layer, granule cell layer, white matter)Cerebellum (white matter)
Cerebellum (white matter)Cerebrum, grey matter – A weak fibrillar MUC1 staining can be seen in samples from the cerebrum.
Cerebrum, grey matter - A weak fibrillar MUC1 staining can be seen in samples from the cerebrum.Cerebrum, grey matter
Cerebrum, grey matterCerebrum, white matter – A weak fibrillar MUC1 staining can be seen in samples from the cerebrum.
Cerebrum, white matter - A weak fibrillar MUC1 staining can be seen in samples from the cerebrum.Cerebrum, white matter
Cerebrum, white matterColon descendens, mucosa
Colon descendens, mucosaColon descendens, muscular wall
Colon descendens, muscular wallDuodenum, Brunner gland – A weak apical membranous staining is occasionally seen in Brunner glands.
Duodenum, Brunner gland - A weak apical membranous staining is occasionally seen in Brunner glands. Duodenum, mucosa
Duodenum, mucosaEpididymis – In the epididymis the staining varies from strong diffuse cytoplasmic with apical predominance to only apical membranous staining. This sample shows a particularly strong staining.
Epididymis - In the epididymis the staining varies from strong diffuse cytoplasmic with apical predominance to only apical membranous staining. This sample shows a particularly strong staining. Esophagus, squamous epithelium – A strong MUC1 immunostaining is seen in this non-keratinizing squamous epithelium of the esophagus.
Esophagus, squamous epithelium - A strong MUC1 immunostaining is seen in this non-keratinizing squamous epithelium of the esophagus. Fallopian tube, mucosa – A strong cytoplasmic MUC1 immunostaining with apical predominance is seen in the epithelium of the fallopian tube.
Fallopian tube, mucosa - A strong cytoplasmic MUC1 immunostaining with apical predominance is seen in the epithelium of the fallopian tube. Fat
FatGallbladder, epithelium – A weak to moderate membranous MUC1 staining is seen in gallbladder epithelium.
Gallbladder, epithelium - A weak to moderate membranous MUC1 staining is seen in gallbladder epithelium.Heart muscle
Heart muscleIleum, mucosa
Ileum, mucosaKidney, cortex – Distal tubuli and collecting ducts show a strong cytoplasmic MUC1 staining while proximal tumuli are completely negative and cells of the Bowman’s capsule show weak to moderate positivity.
Kidney, cortex - Distal tubuli and collecting ducts show a strong cytoplasmic MUC1 staining while proximal tumuli are completely negative and cells of the Bowman’s capsule show weak to moderate positivity. Kidney, medulla – A strong cytoplasmic MUC1 staining is seen in collecting ducts.
Kidney, medulla - A strong cytoplasmic MUC1 staining is seen in collecting ducts. Liver – A weak to moderate, predominantly apical MUC1 staining is seen in intrahepatic bile ducts, while hepatocytes are negative.
Liver - A weak to moderate, predominantly apical MUC1 staining is seen in intrahepatic bile ducts, while hepatocytes are negative. Lung – In the lung, a strong MUC1 staining is seen in all pneumocytes.
Lung - In the lung, a strong MUC1 staining is seen in all pneumocytes. Lymph node – Faint MUC1 staining of few cells in the germinal centre.
Lymph node - Faint MUC1 staining of few cells in the germinal centre. Ovary, stroma
Ovary, stromaPancreas – Pancreatic acinar cells show a strong MUC1 immunostaining of the apical membranes and of granular (Golgi like) structures below the apical surface.
Pancreas - Pancreatic acinar cells show a strong MUC1 immunostaining of the apical membranes and of granular (Golgi like) structures below the apical surface. Parathyroid
ParathyroidParotid gland – In salivary glands, a moderate MUC1 immunostaining of apical membranes of serous glandular cells and of excretory ducts is seen.
Parotid gland - In salivary glands, a moderate MUC1 immunostaining of apical membranes of serous glandular cells and of excretory ducts is seen. Peripheral nerves – Sheaths of peripheral nerves show moderate MUC1 staining.
Peripheral nerves - Sheaths of peripheral nerves show moderate MUC1 staining. Pituitary gland, anterior lobe – In the adenohypophysis a moderate staining with apical predominance is seen in a fraction of cells/acini.
Pituitary gland, anterior lobe - In the adenohypophysis a moderate staining with apical predominance is seen in a fraction of cells/acini.Pituitary gland, posterior lobe – A strong fibrillar MUC1 staining occurs in the neurohypophsis.
Pituitary gland, posterior lobe - A strong fibrillar MUC1 staining occurs in the neurohypophsis.Placenta (amnion and chorion) – A strong cytoplasmic staining is seen in amnion and chorion cells of the placenta.
Placenta (amnion and chorion) - A strong cytoplasmic staining is seen in amnion and chorion cells of the placenta.Placenta, early – In the first trimenon, a predominantly membranous MUC1 staining can occur in a fraction of trophoblastic cells.
Placenta, early - In the first trimenon, a predominantly membranous MUC1 staining can occur in a fraction of trophoblastic cells.Placenta, early – In the first trimenon, a predominantly membranous MUC1 staining can occur in a fraction of trophoblast cells.
Placenta, early - In the first trimenon, a predominantly membranous MUC1 staining can occur in a fraction of trophoblast cells. Placenta, early – A predominantly membranous MUC1 staining can occur in a fraction of trophoblast cells, especially in the first trimenon.
Placenta, early - A predominantly membranous MUC1 staining can occur in a fraction of trophoblast cells, especially in the first trimenon.Placenta, mature – In the mature placenta, a predominantly membranous MUC1 staining can occur in a fraction of trophoblastic cells.
Placenta, mature - In the mature placenta, a predominantly membranous MUC1 staining can occur in a fraction of trophoblastic cells. Placenta, mature – A predominantly membranous MUC1 staining can occur in a fraction of trophoblast cells. In this sample, the staining is strong.
Placenta, mature - A predominantly membranous MUC1 staining can occur in a fraction of trophoblast cells. In this sample, the staining is strong. Prostate – MUC1 immunostaining is variable in the prostate. In this sample, a weak MUC1 staining of luminal cells is seen in few glands while others are completely negative.
Prostate - MUC1 immunostaining is variable in the prostate. In this sample, a weak MUC1 staining of luminal cells is seen in few glands while others are completely negative. Prostate – MUC1 immunostaining is variable in the prostate. In this sample, a moderate to strong MUC1 staining of luminal and basal cells is seen in a fraction of cells of some glands.
Prostate - MUC1 immunostaining is variable in the prostate. In this sample, a moderate to strong MUC1 staining of luminal and basal cells is seen in a fraction of cells of some glands. Rectum, mucosa
Rectum, mucosaSeminal vesicle – A strong apical MUC1 staining focally occurs in seminal vesicle epithelium.
Seminal vesicle - A strong apical MUC1 staining focally occurs in seminal vesicle epithelium. Sinus paranasales – A variable, moderate to strong MUC1 staining occurs in respiratory epithelium.
Sinus paranasales - A variable, moderate to strong MUC1 staining occurs in respiratory epithelium. Skeletal muscle
Skeletal muscleSkin – MUC1 immunostaining is usually absent in the skin.
Skin - MUC1 immunostaining is usually absent in the skin. Skin (sebaceous glands) – A strong MUC1 immunostaining is seen in sebaceous glands, while the skin is usually MUC1 negative.
Skin (sebaceous glands) - A strong MUC1 immunostaining is seen in sebaceous glands, while the skin is usually MUC1 negative. Spleen
SpleenStomach, antrum – Mucous producing glands of the stomach show variable, sometimes also strong MUC1 positivity while the surface epithelial cells of the stomach are largely MUC1 negative.
Stomach, antrum - Mucous producing glands of the stomach show variable, sometimes also strong MUC1 positivity while the surface epithelial cells of the stomach are largely MUC1 negative. Stomach, corpus – Mucous producing glands of the stomach show a strong MUC1 positivity in this sample while the surface epithelial cells are largely MUC1 negative.
Stomach, corpus - Mucous producing glands of the stomach show a strong MUC1 positivity in this sample while the surface epithelial cells are largely MUC1 negative. Testis
TestisThymus – Some elements of corpuscles of Hassall’s show a weak to moderate MUC1 staining.
Thymus - Some elements of corpuscles of Hassall’s show a weak to moderate MUC1 staining. Thyroid gland – A moderate apical MUC1 staining is seen in follicles, sometimes accompanied by a moderate to strong cytoplasmic staining.
Thyroid gland - A moderate apical MUC1 staining is seen in follicles, sometimes accompanied by a moderate to strong cytoplasmic staining. Tonsil – A fraction of squamous epithelial cells of tonsil crypts show a moderate to strong MUC1 staining. Plasma cells are also MUC1 positive.
Tonsil - A fraction of squamous epithelial cells of tonsil crypts show a moderate to strong MUC1 staining. Plasma cells are also MUC1 positive. Tonsil, surface epithelium – A moderate to strong MUC1 immunostaining is seen in this non-keratinizing squamous epithelia of the tonsil surface. The staining is more prominent in the upper than in the basal layers
Tonsil, surface epithelium - A moderate to strong MUC1 immunostaining is seen in this non-keratinizing squamous epithelia of the tonsil surface. The staining is more prominent in the upper than in the basal layersUrinary bladder, muscular wall
Urinary bladder, muscular wallUrinary bladder, urothelium – A moderate to strong MUC1 immunostaining can be seen in the urothelium. The staining is most prominent in the umbrella cells.
Urinary bladder, urothelium - A moderate to strong MUC1 immunostaining can be seen in the urothelium. The staining is most prominent in the umbrella cells. Uterus, ectocervix – A very faint membranous MUC1 immunostaining is seen in this non-keratinizing squamous epithelium from the ectocervix.
Uterus, ectocervix - A very faint membranous MUC1 immunostaining is seen in this non-keratinizing squamous epithelium from the ectocervix. Uterus, endocervix – A strong cytoplasmic MUC1 immunostaining with apical predominance is seen in the endocervical epithelium.
Uterus, endocervix - A strong cytoplasmic MUC1 immunostaining with apical predominance is seen in the endocervical epithelium. Uterus, endometrium (pregnancy) – A strong cytoplasmic MUC1 immunostaining with apical predominance is seen in the pregnant endometrium. Decidua cells are MUC1 negative.
Uterus, endometrium (pregnancy) - A strong cytoplasmic MUC1 immunostaining with apical predominance is seen in the pregnant endometrium. Decidua cells are MUC1 negative.Uterus, endometrium (proliferation) – A very strong MUC1 immunostaining is seen in the endometrium, where the stroma is also often MUC1 positive.
Uterus, endometrium (proliferation) - A very strong MUC1 immunostaining is seen in the endometrium, where the stroma is also often MUC1 positive. Uterus, endometrium (secretion) – A very strong MUC1 immunostaining is seen in the endometrium, where the stroma is also often MUC1 positive.
Uterus, endometrium (secretion) - A very strong MUC1 immunostaining is seen in the endometrium, where the stroma is also often MUC1 positive.Uterus, myometrium
Uterus, myometrium