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Normal Tissue Gallery HLA-DRa
Path
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Adrenal gland
Adrenal gland
Aorta, media
Aorta, media
Appendix, muscular wall
Appendix, muscular wall
Bone marrow
Bone marrow
Breast
Breast
Bronchus, mucosa
Bronchus, mucosa
Bronchus, mucosa: Respiratory epithelium can show a cytoplasmic and membranous HLA-DR immunostaining of variable intensity.
Bronchus, mucosa: Respiratory epithelium can show a cytoplasmic and membranous HLA-DR immunostaining of variable intensity.
Cerebellum (granule cell layer, white matter)
Cerebellum (granule cell layer, white matter)
Cerebellum (molecular, Purkinje, and granule cell layer): In the brain, HLA-DRa immunostaining occurs in cells of monocytic origin.
Cerebellum (molecular, Purkinje, and granule cell layer): In the brain, HLA-DRa immunostaining occurs in cells of monocytic origin.
Cerebrum, grey matter
Cerebrum, grey matter
Cerebrum, white matter
Cerebrum, white matter
Colon descendens, muscular wall
Colon descendens, muscular wall
Duodenum, Brunner gland
Duodenum, Brunner gland
Duodenum, mucosa: The strongest membranous and cytoplasmic epithelial cell HLA-DRa staining occurs in the duodenum.
Duodenum, mucosa: The strongest membranous and cytoplasmic epithelial cell HLA-DRa staining occurs in the duodenum.
Epididymis: A strong cytoplasmic and membranous HLA-DRa immunostaining can be seen in epithelial cells of the epididymis.
Epididymis: A strong cytoplasmic and membranous HLA-DRa immunostaining can be seen in epithelial cells of the epididymis.
Epididymis: In some samples, epithelial cells of the epididymis are lacking HLA-DRa immunostaining.
Epididymis: In some samples, epithelial cells of the epididymis are lacking HLA-DRa immunostaining.
Esophagus, squamous epithelium
Esophagus, squamous epithelium
Fallopian tube, mucosa: A strong, predominantly membranous HLA-DRa immunostaining is regularly seen in a subset of the surface epithelial cells of the fallopian tube (mosaic staining pattern).
Fallopian tube, mucosa: A strong, predominantly membranous HLA-DRa immunostaining is regularly seen in a subset of the surface epithelial cells of the fallopian tube (mosaic staining pattern).
Fat
Fat
Gallbladder, epithelium
Gallbladder, epithelium
Gallbladder, epithelium: A strong cytoplasmic and membranous HLA-DRa staining can occur in the surface epithelium of the gallbladder.
Gallbladder, epithelium: A strong cytoplasmic and membranous HLA-DRa staining can occur in the surface epithelium of the gallbladder.
Heart muscle: In the heart, HLA-DRa staining is seen in endothelial cells of blood vessels.
Heart muscle: In the heart, HLA-DRa staining is seen in endothelial cells of blood vessels.
Ileum, mucosa: A membranous and cytoplasmic HLA-DRa staining of variable intensity is regularly seen in epithelial cells of the ileum.
Ileum, mucosa: A membranous and cytoplasmic epithelial cell HLA-DRa staining of variable intensity is regularly seen in the ileum.
Kidney, cortex: Glomeruli and capillaries show intense HLA-DRa staining.
Kidney, cortex: Glomeruli and capillaries show intense HLA-DRa staining.
Kidney, cortex: A cytoplasmic and membranous HLA-DRa immunostaining can occur in a fraction of tubuli in the kidney.
Kidney, cortex: A cytoplasmic and membranous HLA-DRa immunostaining can occur in a fraction of tubuli in the kidney.
Kidney, medulla
Kidney, medulla
Liver: Sinusoids and Kupffer cells show strong HLA-DRa immunostaining in the liver.
Liver: Sinusoids and Kupffer cells show strong HLA-DRa immunostaining in the liver.
Lung: Intense HLA-DRa immunostaining of alveolar macrophages and alveolar capillaries.
Lung: Intense HLA-DRa immunostaining of alveolar macrophages and alveolar capillaries.
Lymph node: A strong HLA-DRa immunostaining is regularly seen on the majority of inflammatory cells including dendritic cells and macrophages.
Lymph node: A strong HLA-DRa immunostaining is regularly seen on the majority of inflammatory cells including dendritic cells and macrophages.
Ovary, stroma
Ovary, stroma
Pancreas: Excretory ducts may show cytoplasmic and membranous HLA-DRa staining in the pancreas.
Pancreas: Excretory ducts may show cytoplasmic and membranous HLA-DRa staining in the pancreas.
Parathyroid gland
Parathyroid gland
Parotid gland
Parotid gland
Pituitary gland, anterior lobe
Pituitary gland, anterior lobe
Pituitary gland, posterior lobe
Pituitary gland, posterior lobe
Placenta (amnion and chorion)
Placenta (amnion and chorion)
Pregnant uterus (decidua)
Pregnant uterus (decidua)
Placenta, early: Focal HLA-DRa positivity regularly occurs in the early placenta.
Placenta, early: Focal HLA-DRa positivity regularly occurs in the early placenta.
Placenta, mature: Placenta is the only organ without any HLA-DRa positivity of blood vessels.
Placenta, mature: Placenta is the only organ without any HLA-DRa positivity of blood vessels.
Prostate
Prostate
Rectum, mucosa
Rectum, mucosa
Rectum, mucosa
Rectum, mucosa
Seminal vesicle
Seminal vesicle
Sinus paranasales: Respiratory epithelium can show a cytoplasmic and membranous HLA-DRa immunostaining of variable intensity.
Sinus paranasales: Respiratory epithelium can show a cytoplasmic and membranous HLA-DRa immunostaining of variable intensity.
Skeletal muscle: In skeletal muscle, HLA-DRa staining is seen in endothelial cells of blood vessels
Skeletal muscle: In skeletal muscle, HLA-DRa staining is seen in endothelial cells of blood vessels
Skin
Skin
Spleen: A HLA-DRa immunostaining is regularly seen on the majority of inflammatory cells including dendritic cells and macrophages.
Spleen: A HLA-DRa immunostaining is regularly seen on the majority of inflammatory cells including dendritic cells and macrophages.
Stomach, antrum
Stomach, antrum
Stomach, antrum: A cytoplasmic and membranous HLA-DRa staining is often seen in the surface epithelium of the stomach.
Stomach, antrum: A cytoplasmic and membranous HLA-DRa staining is often seen in the surface epithelium of the stomach.
Stomach, corpus
Stomach, corpus
Stomach, corpus: A cytoplasmic and membranous HLA-DRa staining is often seen in the surface epithelium of the stomach.
Stomach, corpus: A cytoplasmic and membranous HLA-DRa staining is often seen in the surface epithelium of the stomach.
Testis
Testis
Thymus: A HLA-DRa immunostaining is regularly seen on the majority of inflammatory cells including dendritic cells and macrophages.
Thymus: A HLA-DRa immunostaining is regularly seen on the majority of inflammatory cells including dendritic cells and macrophages.
Thyroid gland
Thyroid gland
Tonsil: A HLA-DRa immunostaining is regularly seen on the majority of inflammatory cells including dendritic cells and macrophages.
Tonsil: A HLA-DRa immunostaining is regularly seen on the majority of inflammatory cells including dendritic cells and macrophages.
Tonsil, surface epithelium
Tonsil, surface epithelium
Urinary bladder, muscular wall
Urinary bladder, muscular wall
Urinary bladder, urothelium
Urinary bladder, urothelium
Uterus, ectocervix: In the ectocervix, HLA-DRa immunostaining can be seen in endothelial cells and in some inflammatory cells. Note: Surface staining is a result of „inking“ amd not a true immunostaining.
Uterus, ectocervix: In the ectocervix, HLA-DRa immunostaining can be seen in endothelial cells and in some inflammatory cells. Note: Surface staining is a result of „inking“ amd not a true immunostaining.
Uterus, ectocervix: Endocervical epithelium can show a cytoplasmic and membranous HLA-DRa immunostaining of variable intensity.
Uterus, ectocervix: Endocervical epithelium can show a cytoplasmic and membranous HLA-DRa immunostaining of variable intensity.
Uterus, endometrium (proliferation)
Uterus, endometrium (proliferation)
Uterus, endometrium (secretion)
Uterus, endometrium (secretion)
Uterus, myometrium
Uterus, myometrium