Normal Tissue Gallery Estrogen Receptor

Adrenal gland – A very faint ER positivity can be observed in a fraction of adrenocortical cells in this sample.

Adrenal gland – A very faint ER positivity can be observed in a fraction of adrenocortical cells in this sample

Aorta, media – A faint ER staining of muscular cells of the media can occasionally be seen.

Aorta, media – A faint ER staining of muscular cells of the media can occasionally be seen

Appendix, mucosa

Appendix, muscular wall

Bone marrow

Breast – A variable intensity ER staining occurs in a fraction of epithelial cells of the breast gland

Bronchus, mucosa

Cerebellum (molecular layer, Purkinje cell layer, granule cell layer, white matter)

Cerebellum (molecular layer, Purkinje cell layer, granule cell layer)

Cerebrum, grey matter

Cerebrum, white matter

Colon descendens, mucosa

Colon descendens, muscular wall

Duodenum, Brunner gland

Duodenum, mucosa

Epididymis, cauda – A moderate to strong ER immunostaining can be seen in epithelial cells of the cauda epididymis

Epididymis, corpus – ER immunostaining is absent epithelial cells of the corpus epididymis

Esophagus, squamous epithelium – Absence of ER staining in the squamous epithelial cells from this esophageal sample

Fallopian tube, mucosa – A strong epithelial and stromal ER positivity is seen in the fallopian tube

Fat

Gallbladder, epithelium

Heart muscle

Ileum, mucosa

Kidney, cortex

Kidney, medulla

Liver – A variable, weak to moderate ER positivity can be seen in some hepatocytes in a fraction of samples

Liver – ER immunostaining is absent in this liver sample

Lung

Lymph node – In lymphatic tissues, dispersed follicular dendritic cells in germinal centers show a weak to moderate staining

Ovary, stroma – A faint ER immunostaining can be seen in ovarian stroma cells

Pancreas – A very faint ER staining of few islet cells and some other cells of the pancreas can be seen

Parathyroid gland

Parotid gland – A variable, weak to moderate ER positivity can occasionally be seen in a fraction of epithelial cells of salivary glands

Parotid gland

Pituitary gland, anterior lobe – A moderate to strong ER immunostaining can be found in a fraction (10-30%) of epithelial cells in the adenohypophysis

Pituitary gland, posterior lobe

Placenta (amnion)

Placenta (chorion)

Placenta, early

Placenta, mature

Prostate – A moderate to strong ER immunostaining is seen in stromal cells of the prostate

Rectum, mucosa

Seminal vesicle – A moderate to strong ER immunostaining occurs in stromal cells of the seminal vesicles

Sinus paranasales

Skeletal muscle

Skin, hairfollicel and sebaceous glands – A moderate ER staining occurs in peripheral germinative cell of sebaceous glands and in peripheral cells of hair follicles

Skin

Spleen

Stomach, antrum

Stomach, corpus

Testis

Thymus

Thyroid gland

Tonsil, surface epithelium

Urinary bladder, muscular wall

Urinary bladder, urothelium – Weak ER staining in a fraction of urothelial cells, moderate ER staining of some stromal cells

Uterus, cervix – An intense ER staining occurs in stromal cells and in the majority of squamous epithelial cells with a slight decrease of the intensity from the bottom to the top

Uterus, endocervix – ER staining is intense in epithelial and stromal cells of the endocervix

Uterus, endometrium (pregnancy) – A weak to moderate ER immunostaining is seen in decidua cells

Uterus, endometrium (proliferation) – ER immunostaining is at its highest level in epithelial and stromal cells of the endometrium

Uterus, endometrium (secretion) – ER immunostaining is stronger in epithelial than in stromal cells of this sample of this endometrium in secretion phase

Uterus, myometrium – Strong ER staining of the myometrium muscle cells