Adrenal gland – In the adrenal gland, EpCAM staining can be very faint or even absent.
Adrenal gland - In the adrenal gland, EpCAM staining can be very faint or even absent.
Adrenal gland – In the adrenal gland, a weak membranous staining of adrenocortical cells can be seen.
Adrenal gland - In the adrenal gland, a weak membranous staining of adrenocortical cells can be seen.
Aorta, media
Aorta, media Appendix, mucosa
Appendix, mucosa Appendix, muscular wall
Appendix, muscular wall Bone marrow
Bone marrow Breast – In the breast gland, luminal cells are strongly positive but basal/myoepithelial cells show much less or absent staining.
Breast - In the breast gland, luminal cells are strongly positive but basal/myoepithelial cells show much less or absent staining.
Bronchus, mucosa
Bronchus, mucosa Cerebellum (granule cell layer, white matter)
Cerebellum (granule cell layer, white matter)Cerebellum (molecular layer, Purkinje cell layer, granule cell layer)
Cerebellum (molecular layer, Purkinje cell layer, granule cell layer)Cerebrum, grey matter
Cerebrum, grey matter Cerebrum, white matter
Cerebrum, white matter Colon descendens, mucosa
Colon descendens, mucosa Colon descendens, muscular wall
Colon descendens, muscular wall Duodenum, Brunner gland
Duodenum, Brunner gland Duodenum, mucosa
Duodenum, mucosaEpididymis
EpididymisEsophagus, squamous epithelium – A weak to moderate EpCam immunostaining is seen in the suprabasal cell layers of esophageal squamous epithelium.
Esophagus, squamous epithelium - A weak to moderate EpCam immunostaining is seen in the suprabasal cell layers of esophageal squamous epithelium.
Fallopian tube, mucosa
Fallopian tube, mucosa Fat
FatGallbladder, epithelium
Gallbladder, epithelium Heart muscle
Heart muscle Ileum, mucosa
Ileum, mucosa Kidney, cortex – In the kidney, a strong staining is seen in the distal tubuli while staining is less intense and focussed to the basolateral membranes in the majority of proximal tubulus cells. Scattered epithelial cells lining the Bowman capsule are also positive.
Kidney, cortex - In the kidney, a strong staining is seen in the distal tubuli while staining is less intense and focussed to the basolateral membranes in the majority of proximal tubulus cells. Scattered epithelial cells lining the Bowman capsule are also positive.
Kidney, medulla
Kidney, medulla Liver – In the liver, hepatocytes are EpCAM negative but EpCAM is strongly expressed in epithelial cells of the bile ducts.
Liver - In the liver, hepatocytes are EpCAM negative but EpCAM is strongly expressed in epithelial cells of the bile ducts.
Lung – In the lung, a weak to moderate EpCAM immunostaining is seen in pneumocytes.
Lung - In the lung, a weak to moderate EpCAM immunostaining is seen in pneumocytes.
Lymph node
Lymph node Ovary, stroma
Ovary, stroma Ovary, stroma – A strong EpCAM immunostaining is seen in oocytes of the ovary.
Ovary, stroma - A strong EpCAM immunostaining is seen in oocytes of the ovary.
Pancreas
Pancreas Parathyroid gland
Parathyroid gland Parotid gland
Parotid glandPituitary gland, anterior lobe
Pituitary gland, anterior lobe Pituitary gland, posterior lobe
Pituitary gland, posterior lobePlacenta, first trimester – In the first trimester placenta only cytotrophoblast cells shows a weak to moderate EpCAM staining.
Placenta, first trimester - In the first trimester placenta only cytotrophoblast cells shows a weak to moderate EpCAM staining.
Placenta, mature – In the mature placenta, a weak membranous staining of the basal membrane of the trophoblast layer is occasionally seen.
Placenta, mature - In the mature placenta, a weak membranous staining of the basal membrane of the trophoblast layer is occasionally seen.
Placenta, mature, amnion and chorion – EpCam immunostaining is moderate in chorion cells and weak in amnion cells of the placenta.
Placenta (amnion and chorion) - EpCam immunostaining is moderate in chorion cells and weak in amnion cells of the placenta.
Prostate
ProstateRectum, mucosa
Rectum, mucosa Seminal vesicle
Seminal vesicle Sinus paranasales
Sinus paranasalesSkeletal muscle
Skeletal muscle Skin
SkinSpleen
SpleenStomach, antrum
Stomach, antrum Stomach, corpus – EpCAM is strongly expressed in epithelial cells of the stomach. Only parietal cells show a weaker staining limited to the basolateral membranes.
Stomach, corpus - EpCAM is strongly expressed in epithelial cells of the stomach. Only parietal cells show a weaker staining limited to the basolateral membranes.
Testis – In the testis, spermatogonia and spermatocytes show strong EpCAM immunostaining but Sertoli and Leydig cells are negative.
Testis - In the testis, spermatogonia and spermatocytes show strong EpCAM immunostaining but Sertoli and Leydig cells are negative.
Thymus – Most thymus epithelial cells including corpuscles of Hassall’s show a weak to moderate EpCAM positivity.
Thymus - Most thymus epithelial cells including corpuscles of Hassall’s show a weak to moderate EpCAM positivity.
Thyroid gland
Thyroid gland Tonsil – A moderate EpCAM positivity is seen in a subset of squamous epithelial cells of the tonsil crypts.
Tonsil - A moderate EpCAM positivity is seen in a subset of squamous epithelial cells of the tonsil crypts.
Tonsil, surface epithelium – A weak to moderate EpCam immunostaining is seen in the basal cell layers of squamous epithelium of the tonsil surface.
Tonsil, surface epithelium - A weak to moderate EpCam immunostaining is seen in the basal cell layers of squamous epithelium of the tonsil surface.
Urinary bladder, muscular wall
Urinary bladder, muscular wallUrinary bladder, urothelium
Urinary bladder, urothelium Uterus, ectocervix – A weak EpCam positivity is seen in the basal cell layer of squamous epithelium of the ectocervix.
Uterus, ectocervix - A weak EpCam positivity is seen in the basal cell layer of squamous epithelium of the ectocervix.
Uterus, endocervix
Uterus, endocervix Uterus, endometrium (pregnancy)
Uterus, endometrium (pregnancy)Uterus, endometrium (proliferation)
Uterus, endometrium (proliferation) Uterus, endometrium (secretion)
Uterus, endometrium (secretion) Uterus, myometrium
Uterus, myometrium