Adrenal gland
Aorta, media
Appendix, mucosa - Strong KRT19 staining of epithelial cells in the appendix. Slight decrease of intensity from the surface towards the crypt base.
Appendix, muscular wall
Bone marrow
Breast - Intensive KRT19 staining of a fraction of luminal cells.
Bronchus, mucosa - Stronk KRT19 staining of all epithelial cells.
Cerebellum, cortex (Stratum moleculare) cerebellum (molecular layer, Purkinje cell layer, granule cell layer)
Cerebellum, cortex (Stratum moleculare) cerebellum (granule cell layer, white matter)
Cerebrum, grey matter
Cerebrum, white matter
Colon descendens, mucosa - Strong KRT19 staining of all epithelial cells.
Colon descendens, muscular wall
Duodenum, Brunner gland - A variable, usually weak cytokeratin 19 staining is seen in a fraction of cells in Brunner glands.
Duodenum, mucosa - KRT 19 staining is stronger at the surface mucosa than in deeper located glandular cells.
Ectocervix - In non-keratinizing squamous epithelium, the basal cells are CK19 positive while the remaining layers are usually negative.
Endocervix - Strong KRT19 staining of all epithelial cells.
Endometrium, secretion - Strong KRT19 staining of all epithelial cells.
Epididymis - Strong KRT19 staining of all epithelial cells.
Esophagus, squamous epithelium - KRT19 staining is usually limited to the basal cells. In this sample some additional "higher" KRT19 positive squamous cells are seen.
Fallopian tube, mucosa - Strong KRT19 staining of all epithelial cells.
Fat
Gallbladder, epithelium - Strong KRT19 staining of all epithelial cells.
Heart
Ileum, mucosa - Strong KRT19 staining of all epithelial cells.
Kidney, cortex - In the kidney, a large fraction of the cells of the distal tubuli and collecting ducts as well as parietal epithelial cells of the Bowman capsule show strong Cytokeratin 19 immunostaining.
Kidney, medulla - A large fraction of the cells of collecting ducts show strong Cytokeratin 19 staining.
Liver - A strong KRT19 staining is seen in bile ducts including small periportal ducts.
Lung- Pneumocytes show a moderate KRT19 staining.
Lymph node
Ovary, stroma
Pancreas - KRT19 positivity is seen in interlobular and intercalated ducts of the pancreas.
Parathyroid gland - All epithelial cells show at least a moderate KRT19 staining.
Parotid gland - In salivary glands, cytokeratin 19 is seen in intercalated and striated ducts, myoepithelial cells (and to a lesser and variable extent) glandular cells of salivary glands.
Pituitary gland, anterior lobe
Pituitary gland, posterior lobe
Pregnant uterus (decidua)
Placenta, early
Placenta, mature - The syncytiotrophoblast, and to a somewhat lesser extent the cytotrophoblast of the placenta are KRT19 positive.
Placenta (amnion and chorion) - Amnion and chorion cells of the placenta are cytokeratin positive.
Prostate - A variable cytokeratin 19 staining intensity of both apical and basal cells can occur in the prostate but not in all glands and not in all samples.
Rectum, mucosa - Strong KRT19 staining of all epithelial cells.
Seminal vesicle - Strong KRT19 staining of all epithelial cells.
Sinus paranasales - Strong KRT19 staining of all epithelial cells.
Skin
Spleen
Stomach, antrum - Strong KRT19 staining of all epithelial cells.
Stomach, corpus - CK19 staining is strong in most epithelial cells of the stomach corpus except staining being absent in parietal cells and only weak in chief cells.
Striated muscle
Testis
Tonsil - A strong CK19 positivity is seen in some but not all squamous cells of tonsil crypts.
Tonsil, surface epithelium - KRT19 staining is largely limited to the basal cells of the squamous epithelium.
Thyroid gland
Urinary bladder, muscular wall
Urinary bladder - Urothelium always shows a strong CK19 positivity of all epithelial cells.
Uterus, myometrium - A weak to moderate cytokeratin 19 immunostaining can be seen in smooth muscle of the myometrium.
Uterus, myometrium - Cytokeratin 19 positivity is not always seen in myometrium.