Adrenal gland – Strong granular cytoplasmic CTLA-4 immunostaining of adrenocortical cells (tolerable cross-reactivity). Staining is absent in medullary cells.
Adrenal gland - Strong granular cytoplasmic CTLA-4 immunostaining of adrenocortical cells (tolerable cross-reactivity). Staining is absent in medullary cells.Adrenal gland – Weak to moderate granular cytoplasmic CTLA-4 immunostaining of adrenocortical cells (tolerable cross-reactivity).
Adrenal gland - Weak to moderate granular cytoplasmic CTLA-4 immunostaining of adrenocortical cells (tolerable cross-reactivity).Aorta, media
Aorta, media Appendix, mucosa – Distinct CTLA-4 immunostaining in a fraction of lymphocytes. In addition, weak apical cytoplasmic granular CTLA-4 staining occurs in superficial epithelial cells (tolerable cross-reactivity)
Appendix, mucosa - Distinct CTLA-4 immunostaining in a fraction of lymphocytes. In addition, weak apical cytoplasmic granular CTLA-4 staining occurs in superficial epithelial cells (tolerable cross-reactivity)Appendix, muscular wall
Appendix, muscular wall Bone marrow
Bone marrowBreast
BreastBronchus, mucosa
Bronchus, mucosaCerebellum (molecular layer, Purkinje cell layer, granule cell layer, white matter) – Faint fibrillar CTLA-4 immunostaining of the molecular layer (tolerable cross-reactivity).
Cerebellum (molecular layer, Purkinje cell layer, granule cell layer, white matter) - Faint fibrillar CTLA-4 immunostaining of the molecular layer (tolerable cross-reactivity).Cerebellum (molecular layer, Purkinje cell layer, granule cell layer) – A faint fibrillar CTLA-4 immunostaining of the molecular layer may reflect a (tolerable) cross-reactivity.
Cerebellum (molecular layer, Purkinje cell layer, granule cell layer) - A faint fibrillar CTLA-4 immunostaining of the molecular layer may reflect a (tolerable) cross-reactivity.Cerebrum, grey matter
Cerebrum, grey matterCerebrum, white matter
Cerebrum, white matterColon descendens, mucosa – Weak apical cytoplasmic granular CTLA-4 immunostaining in superficial epithelial cells (tolerable cross-reactivity).
Colon descendens, mucosa - Weak apical cytoplasmic granular CTLA-4 immunostaining in superficial epithelial cells (tolerable cross-reactivity).Colon descendens, muscular wall
Colon descendens, muscular wall Duodenum, Brunner gland
Duodenum, Brunner glandDuodenum, mucosa – Apical cytoplasmic granular CTLA-4 positivity in superficial epithelial cells (tolerable cross-reactivity).
Duodenum, mucosa - Apical cytoplasmic granular CTLA-4 positivity in superficial epithelial cells (tolerable cross-reactivity).Epididymis – Weak apical cytoplasmic granular CTLA-4 immunostaining in tall columnar cells of the epididymis (tolerable cross-reactivity).
Epididymis - Weak apical cytoplasmic granular CTLA-4 immunostaining in tall columnar cells of the epididymis (tolerable cross-reactivity).Esophagus, squamous epithelium
Esophagus, squamous epithelium Fallopian tube, mucosa
Fallopian tube, mucosaFat
FatGallbladder, epithelium – Weak apical cytoplasmic granular CTLA-4 immunostaining in epithelial cells (tolerable cross-reactivity).
Gallbladder, epithelium - Weak apical cytoplasmic granular CTLA-4 immunostaining in epithelial cells (tolerable cross-reactivity).Heart muscle
Heart muscle Ileum, mucosa – Weak apical cytoplasmic granular CTLA-4 immunostaining in superficial epithelial cells of the stomach (tolerable cross-reactivity).
Ileum, mucosa - Weak apical cytoplasmic granular CTLA-4 immunostaining in superficial epithelial cells of the stomach (tolerable cross-reactivity).Kidney, cortex – Granular CTLA-4 staining in a small fraction of renal tubuli (tolerable cross-reactivity).
Kidney, cortex - Granular CTLA-4 staining in a small fraction of renal tubuli (tolerable cross-reactivity).Kidney, cortex
Kidney, cortexKidney, medulla
Kidney, medullaLiver – Weak granular CTLA-4 staining of pigment.
Liver - Weak granular CTLA-4 staining of pigment.Lung
LungLymph node – CTLA-4 immunostaining in a fraction of lymphocytes.
Lymph node - CTLA-4 immunostaining in a fraction of lymphocytes. Ovary, stroma
Ovary, stroma Pancreas – Weak apical cytoplasmic granular CTLA-4 staining in acinar cells and in excretory duct epithelial cells (tolerable cross-reactivity).
Pancreas - Weak apical cytoplasmic granular CTLA-4 staining in acinar cells and in excretory duct epithelial cells (tolerable cross-reactivity).Pancreas
PancreasParathyroid gland
Parathyroid glandParotid gland
Parotid glandPituitary gland, anterior lobe
Pituitary gland, anterior lobe Pituitary gland, posterior lobe
Pituitary gland, posterior lobePlacenta (amnion and chorion)
Placenta (amnion and chorion) Placenta, early
Placenta, earlyPlacenta, mature
Placenta, matureProstate
ProstateRectum, mucosa
Rectum, mucosaSeminal vesicle
Seminal vesicleSinus paranasales – A fraction of mucosa associated lymphocytes shows distinct CTLA-4 positivity.
Sinus paranasales - A fraction of mucosa associated lymphocytes shows distinct CTLA-4 positivity.Skeletal muscle
Skeletal muscle Skin
SkinSpleen – CTLA-4 immunostaining in a fraction of lymphocytes.
Spleen - CTLA-4 immunostaining in a fraction of lymphocytes. Stomach, antrum – Apical cytoplasmic granular CTLA-4 immunostaining in superficial epithelial cells of the stomach (tolerable cross-reactivity).
Stomach, antrum - Apical cytoplasmic granular CTLA-4 immunostaining in superficial epithelial cells of the stomach (tolerable cross-reactivity).Stomach, corpus – Weak apical cytoplasmic granular CTLA-4 immunostaining in some superficial epithelial cells of the stomach (tolerable cross-reactivity).
Stomach, corpus - Weak apical cytoplasmic granular CTLA-4 immunostaining in some superficial epithelial cells of the stomach (tolerable cross-reactivity).Testis
TestisThymus – CTLA-4 positivity in a fraction of lymphocytes.
Thymus - CTLA-4 positivity in a fraction of lymphocytes.Thymus – CTLA-4 staining in a fraction of lymphocytes.
Thymus - CTLA-4 staining in a fraction of lymphocytes.Thyroid gland – CTLA-4 immunostaining of kolloid. This may represent a (tolerable) cross-reactivity.
Thyroid gland - CTLA-4 immunostaining of kolloid. This may represent a (tolerable) cross-reactivity.Tonsil – A distinct CTLA-4 immunostaining is seen in a fraction of lymphocytes.
Tonsil - A distinct CTLA-4 immunostaining is seen in a fraction of lymphocytes.Tonsil – CTLA-4 immunostaining of a subset of lymphocytes (predominantly interfollicular).
Tonsil - CTLA-4 immunostaining of a subset of lymphocytes (predominantly interfollicular).Tonsil – Distinct CTLA-4 positivity in a fraction of lymphocytes.
Tonsil - Distinct CTLA-4 positivity in a fraction of lymphocytes. Tonsil, surface epithelium – Distinct staining of a subset of lymphocytes.
Tonsil, surface epithelium - Distinct staining of a subset of lymphocytes.Urinary bladder, muscular wall
Urinary bladder, muscular wallUrinary bladder, urothelium – CTLA-4 positivity of a subset of mucosa associated lymphocytes.
Urinary bladder, urothelium - CTLA-4 positivity of a subset of mucosa associated lymphocytes. Urinary bladder, urothelium
Urinary bladder, urothelium Uterus, ectocervix
Uterus, ectocervixUterus, endocervix
Uterus, endocervixUterus, endometrium (pregnancy) – Granular cytoplasmic CTLA-4 immunostaining of decidua cells (tolerable cross-reactivity).
Uterus, endometrium (pregnancy) - Granular cytoplasmic CTLA-4 immunostaining of decidua cells (tolerable cross-reactivity).Uterus, endometrium (proliferation)
Uterus, endometrium (proliferation)Uterus, endometrium (secretion)
Uterus, endometrium (secretion)Uterus, myometrium
Uterus, myometrium