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Normal Tissue Gallery Chromogranin A
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Adrenal gland - Chromogranin A staining is absent in the cortex.
Adrenal gland – Chromogranin A staining is absent in the cortex.
Adrenal gland - Intense chromogranin A staining in all cells of the medulla.
Adrenal gland – Intense chromogranin A staining in all cells of the medulla.
Aorta, media
Aorta, media
Appendix, mucosa
Appendix, mucosa
Appendix, muscular wall - Weak chromogranin A immunostaining is seen in axons and ganglion cells of the peripheral nerves.
Appendix, muscular wall – Weak chromogranin A immunostaining is seen in axons and ganglion cells of the peripheral nerves.
Bone marrow
Bone marrow
Breast
Breast
Cerebellum (molecular layer, Purkinje cell layer, granule cell layer, white matter)
Cerebellum (molecular layer, Purkinje cell layer, granule cell layer, white matter)
Cerebellum (granule cell layer, white matter)
Cerebellum (granule cell layer, white matter)
Cerebrum, grey matter
Cerebrum, grey matter
Cerebrum, white matter
Cerebrum, white matter
Colon descendens, mucosa
Colon descendens, mucosa
Colon descendens, muscular wall
Colon descendens, muscular wall
Duodenum, Brunner gland
Duodenum, Brunner gland
Duodenum, mucosa - Strong chromogranin A immunostaining of neuroendocrine cells. Due to the high level of chromogranin A protein in these cells, adjacent non-neuroendocrine cells show "contamination artifacts".
Duodenum, mucosa – Strong chromogranin A immunostaining of neuroendocrine cells. Due to the high level of chromogranin A protein in these cells, adjacent non-neuroendocrine cells show “contamination artifacts”.
Ectocervix
Ectocervix
Endocervix
Endocervix
Endocervix - Few neuroendocrine cells are chromogranin A positive.
Endocervix – Few neuroendocrine cells are chromogranin A positive.
Endometrium, proliferation
Endometrium, proliferation
Endometrium, secretion
Endometrium, secretion
Epididymis
Epididymis
Esophagus, squamous epithelium
Esophagus, squamous epithelium
Fallopian tube, mucosa
Fallopian tube, mucosa
Fat
Fat
Gallbladder, epithelium
Gallbladder, epithelium
Heart
Heart
Ileum, mucosa
Ileum, mucosa
Kidney, cortex
Kidney, cortex
Kidney, medulla
Kidney, medulla
Liver
Liver
Lung
Lung
Lymph node
Lymph node
Ovary, stroma
Ovary, stroma
Pancreas - Strong chromogranin A positivity in islets of Langerhans.
Pancreas – Strong chromogranin A positivity in islets of Langerhans.
Parathyroid gland - Strong chromogranin A staining of epithelial cells.
Parathyroid gland – Strong chromogranin A staining of epithelial cells.
Parotid gland
Parotid gland
Pituitary gland, anterior lobe - Strong chromogranin A staining of epithelial cells.
Pituitary gland, anterior lobe – Strong chromogranin A staining of epithelial cells.
Pituitary gland, posterior lobe
Pituitary gland, posterior lobe
Pregnant uterus (decidua)
Pregnant uterus (decidua)
Placenta, early
Placenta, early
Placenta, mature
Placenta, mature
Placenta (amnion and chorion)
Placenta (amnion and chorion)
Prostate
Prostate
Seminal vesicle
Seminal vesicle
Sinus paranasales
Sinus paranasales
Skin - Few neuroendokrine (Merkel-) cells show chromogranin A immunostaining.
Skin – Few neuroendokrine (Merkel-) cells show chromogranin A immunostaining.
Spleen
Spleen
Stomach, antrum
Stomach, antrum
Stomach, corpus
Stomach, corpus
Stomach, corpus - Expression of chromogranin A is so strong in neuroendocrine cells of the stomach, that diffusion of the staining product towards adjacent cells can occur.
Stomach, corpus – Expression of chromogranin A is so strong in neuroendocrine cells of the stomach, that diffusion of the staining product towards adjacent cells can occur.
Testis
Testis
Thymus
Thymus
Thyroid gland
Thyroid gland
Tongue, muscle
Tongue, muscle
Tonsil, surface epithelium
Tonsil, surface epithelium
Tonsil
Tonsil
Urinary bladder, muscular wall
Urinary bladder, muscular wall
Urinary bladder, urothelium
Urinary bladder, urothelium
Uterus, myometrium
Uterus, myometrium