Adrenal gland – TFF1 negative adrenocortical adenoma
Breast – Invasive breast cancer of no special type (NST) with strong TFF1 immunostaining of most tumor cells
Colon - Colorectal adenocarcinoma with weak to moderate TFF1 positivity of most tumor cells
Esophagus – Adenocarcinoma with strong TFF1 positivity of tumor cells
Esophagus – TFF1 negative squamous cell carcinoma
Kidney – TFF1 negative clear cell carcinoma
Kidney –TFF1 negative papillary renal cell carcinoma
Liver – Cholangiocellular carcinoma with strong TFF1 positivity of all tumor cells
Liver – TFF1 negative hepatocellular carcinoma
Lung – Mucinous adenocarcinoma with moderate to strong TFF1 staining of most tumor cells
Lung – TFF1 negative squamous cell carcinoma
Lymph node – TFF1 negative diffuse large B-cell lymphoma
Lymph node – TFF1 negative Hodgkin’s lymphoma
Oral cavity – TFF1 negative squamous cell carcinoma
Ovary – Mucinous carcinoma with intense TFF1 immunostaining of tumor cells
Ovary – TFF1 negative clear cell carcinoma
Ovary – TFF1 negative serous high-grade carcinoma
Pancreas – Ductal adenocarcinoma with strong TFF1 staining of all tumor cells
Pancreas – Neuroendocrine tumor with strong TFF1 staining of tumor cells
Prostate – Adenocarcinoma (Gleason 4+4=8) with moderate to strong TFF1 staining of a large fraction of tumor cells
Prostate –TFF1 negative adenocarcinoma (Gleason 3+3=6)
Salivary gland – TFF1 negative Warthin tumor
Skin – TFF1 negative basal cell carcinoma
Stomach – Gastric adenocarcinoma (diffuse type) with intense TFF1 immunostaining of all tumor cells
Stomach – Gastric adenocarcinoma (intestinal type) with moderate TFF1 staining of a subset of tumor cells
Stomach – TFF1 negative gastrointestinal stromal tumor (GIST)
Testis – TFF1 negative seminoma
Thyroid – Papillary carcinoma with “dot-like” perinuclear TFF1 staining of a fraction of tumor cells
Thyroid – TFF1 negative medullary carcinoma
Urinary bladder – Muscle-invasive urothelial carcinoma with moderate to strong TFF1 immunostaining of most tumor cells
Urinary bladder – Non-invasive urothelial carcinoma (low grade, pTaG2) with moderate to strong TFF1 immunostaining of a significant subset of tumor cells
Uterus, cervix – Adenocarcinoma with moderate to strong TFF1 immunostaining of tumor cells
Uterus, cervix – Adenocarcinoma with strong TFF1 staining of most tumor cells