Cancer Tissue Gallery PD-L1

Breast - Breast cancer NST with PD-L1 negative tumor cells but intense PD-L1 staining in tumor associated inflammatory cells.

Breast – Breast cancer NST with PD-L1 negative tumor cells but intense PD-L1 staining in tumor associated inflammatory cells.

Breast - Breast cancer NST with PD-L1 negative tumor cells. Tumor associated inflammatory cells show strongest PD-L1 staining if they are immediately adjacent to tumor cells.

Breast – Breast cancer NST with PD-L1 negative tumor cells. Tumor associated inflammatory cells show strongest PD-L1 staining if they are immediately adjacent to tumor cells.

Colon - Colorectal adenocarcinoma with moderate to strong membranous PD-L1 staining in the vast majority of its tumor cells.

Colon – Colorectal adenocarcinoma with moderate to strong membranous PD-L1 staining in the vast majority of its tumor cells.

Colon - Colorectal adenocarcinoma with PD-L1 negative tumor cells surrounded by large numbers of tumor associated inflammatory cells with intense PD-L1 staining.

Colon – Colorectal adenocarcinoma with PD-L1 negative tumor cells surrounded by large numbers of tumor associated inflammatory cells with intense PD-L1 staining.

Colon - Colorectal adenocarcinoma with PD-L1 staining limited to intraglandular macrophages.

Colon – Colorectal adenocarcinoma with PD-L1 staining limited to intraglandular macrophages.

Kidney - Weak to moderate membranous PD-L1 staining in a clear cell renal cell carcinoma.

Kidney – Weak to moderate membranous PD-L1 staining in a clear cell renal cell carcinoma.

Lymph node - Strong PD-L1 immunostaining in all tumor cells of an anaplastic large cell lymphoma.

Lymph node – Strong PD-L1 immunostaining in all tumor cells of an anaplastic large cell lymphoma.

Ovary - Few scattered PD-L1 positive cells in a mucinous ovarian cancer. Most likely, these cells are tumor associated macrophages.

Ovary – Few scattered PD-L1 positive cells in a mucinous ovarian cancer. Most likely, these cells are tumor associated macrophages.

Prostate - Few scattered cells (tumor cells or tumor associated macrophages) with membranous PD-L1 staining in a recurrent Gleason 5+5 adenocarcinoma of the prostate.

Prostate – Few scattered cells (tumor cells or tumor associated macrophages) with membranous PD-L1 staining in a recurrent Gleason 5+5 adenocarcinoma of the prostate.

Prostate - Moderate to strong membranous PD-L1 staining in virtually all tumor cells of a Gleason 5+5 prostate cancer.

Prostate – Moderate to strong membranous PD-L1 staining in virtually all tumor cells of a Gleason 5+5 prostate cancer.

Skin - Strong focal PD-L1 staining in tumor associated inflammatory cells in a basal cell carcinoma of the skin. PD-L1 staining is not seen in tumor cells.

Skin – Strong focal PD-L1 staining in tumor associated inflammatory cells in a basal cell carcinoma of the skin. PD-L1 staining is not seen in tumor cells.

Stomach - Strong PD-L1 positivity in all tumor cells of a gastrointestinal stromal tumor (GIST).

Stomach – Strong PD-L1 positivity in all tumor cells of a gastrointestinal stromal tumor (GIST).

Thyroid - Follicular thyroid cancer with moderate to strong membranous PD-L1 staining.

Thyroid – Follicular thyroid cancer with moderate to strong membranous PD-L1 staining.

Urinary bladder - Non-invasive papillary urothelial carcinoma with moderate PD-L1 staining which is strictly limited to the basal cell layer. Absence of tumor associated inflammatory cells.

Urinary bladder – Non-invasive papillary urothelial carcinoma with moderate PD-L1 staining which is strictly limited to the basal cell layer. Absence of tumor associated inflammatory cells.

Urinary bladder - Urothelial carcinoma with PD-L1 negative tumor cells containing large numbers of PD-L1 positive tumor associated inflammatory cells.

Urinary bladder – Urothelial carcinoma with PD-L1 negative tumor cells containing large numbers of PD-L1 positive tumor associated inflammatory cells.

Urinary bladder - Urothelial carcinoma with prominent PD-L1 staining in tumor associated inflammatory cells. In addition, few tumor cells show faint membranous staining.

Urinary bladder – Urothelial carcinoma with prominent PD-L1 staining in tumor associated inflammatory cells. In addition, few tumor cells show faint membranous staining.

Vulva - Weak to moderate membranous PD-L1 positivity in the majority of tumor cells of a squamous cell carcinoma of the vulva.

Vulva – Weak to moderate membranous PD-L1 positivity in the majority of tumor cells of a squamous cell carcinoma of the vulva.