Breast – Invasive breast cancer of no special type (NST) with strong cytoplasmic and membranous GPRC5A immunostaining of tumor cells.
Breast – Invasive breast cancer of no special type (NST) with strong cytoplasmic and membranous GPRC5A positivity of tumor cells.
Breast – Invasive lobular breast cancer with moderate to strong “pan-membranous” GPRC5A positivity of tumor cells.
Colon – Colorectal adenocarcinoma with intense, predominantly cytoplasmic GPRC5A staining of tumor cells.
Colon – Colorectal adenocarcinoma with strong GPRC5A staining of tumor cells, primarily involving the luminal membranes.
Kidney – GPRC5A negative clear cell carcinoma.
Kidney – GPRC5A negative oncocytoma.
Kidney – GPRC5A negative papillary renal cell carcinoma.
Lung – Adenocarcinoma with strong “pan-membranous” GPRC5A positivity of tumor cells.
Lung – Adenocarcinoma with strong GPRC5A staining of apical and lateral membranes of all tumor cells. .jpeg
Lung – GPRC5A negative malignant mesothelioma.
Lung – Malignant mesothelioma with “pan-membranous” GPRC5A positivity of tumor cells at variable intensity.
Lung – Malignant mesothelioma with distinct GPRC5A staining of luminal membranes of a subset of tumor cells.
Lung – Squamous cell carcinoma with strong “pan-membranous” GPRC5A positivity of tumor cells.
Oral cavity – Squamous cell carcinoma with strong membranous and cytoplasmic GPRC5A positivity of tumor cells.
Ovary – Clear cell carcinoma with moderate to strong GPRC5A staining of luminal membranes of a subset of tumor cells.
Ovary – Endometroid carcinoma with strong GPRC5A staining of luminal membranes of tumor cells.
Ovary – Serous high-grade carcinoma with strong GPRC5A immunostaining of luminal membranes of a subset of tumor cells.
Pharynx – Squamous cell carcinoma with variable intensity (weak to strong), predominantly membranous GPRC5A staining of tumor cells.
Prostate – Adenocarcinoma (Gleason 3+3=6) with strong GPRC5A staining of luminal membranes of most cancer cells.
Testis – GPRC5A negative seminoma.
Testis – Seminoma with strong, predominantly cytoplasmic GPRC5A staining of tumor cells.
Thyroid – Papillary cancer with intense GPRC5A positivity of luminal membranes of all tumor cells.
Urinary bladder – Micropapillary muscle-invasive urothelial carcinoma with strong GPRC5A staining of the surface membranes of small “micropapillary tumor cell groups”.
Urinary bladder – Muscle-invasive urothelial carcinoma with strong membranous and cytoplasmic GPRC5A positivity of tumor cells. .jpeg
Urinary bladder – Non-invasive urothelial carcinoma (low grade, pTaG2) displaying a distinct, predominantly membranous GPRC5A staining of (predominantly basal) tumor cells.
Urinary bladder – Non-invasive urothelial carcinoma (low grade, pTaG2) with strong GPRC5A staining of tumor cells.