Cancer Tissue Gallery Androgen Receptor

Adrenal gland – AR negative adrenocortical adenoma.

Breast – Invasive breast cancer of no special type (NST) with moderate to strong AR immunostaining of tumor cells.

Breast – Invasive lobular breast cancer with strong AR immunostaining of tumor cells.

Colon – AR negative colorectal adenocarcinoma.

Esophagus – AR negative adenocarcinoma.

Esophagus – AR negative squamous cell carcinoma.

Kidney – AR negative clear cell renal cell carcinoma.

Kidney – AR negative oncocytoma.

Kidney – Papillary renal cell carcinoma with moderate to strong AR immunostaining of tumor cells.

Liver – AR negative cholangiocellular carcinoma.

Liver – Hepatocellular carcinoma with moderate to strong AR immunostaining of tumor cells.

Lung – AR negative adenocarcinoma.

Ovary – AR negative clear cell carcinoma.

Ovary – Serous high-grade carcinoma with moderate AR immunostaining of tumor cells.

Pancreas – AR negative ductal adenocarcinoma.

Pancreas – AR negative neuroendocrine tumor.

Pharynx – AR negative squamous cell carcinoma.

Prostate – Adenocarcinoma (Gleason 4+4=8) showing strong AR immunostaining of tumor cells. Of note: AR staining is weaker in one residual normal prostate gland.

Prostate – Adenocarcinoma (Gleason 4+4=8) with strong AR immunostaining.

Prostate – Adenocarcinoma (Gleason 5+5=10) with strong nuclear and cytoplasmic AR immunostaining of tumor cells.

Prostate – Recurrent adenocarcinoma of the prostate (Gleason 5+4=9) with subtotal loss of AR expression after castration therapy.

Prostate – Small cell carcinoma with focal weak to moderate AR immunostaining of tumor cells.

Soft tissue – AR negative leiomyosarcoma.

Stomach – AR negative gastric adenocarcinoma (diffuse type).

Stomach – AR negative gastric adenocarcinoma.

Stomach – AR negative gastrointestinal stromal tumor (GIST).

Testis – AR negative seminoma.

Thorax – AR negative epitheloid malignant mesothelioma.

Thyroid – AR negative medullary carcinoma.

Thyroid – AR negative papillary cancer.

Urinary bladder – Muscle-invasive urothelial carcinoma with focal weak AR immunostaining in <10% of tumor cells.

Urinary bladder – Muscle-invasive urothelial carcinoma with moderate to strong AR immunostaining of tumor cells.

Uterus – Endometroid endometrium carcinoma with AR immunostaining of variable intensity in the majority of tumor cells.