Adrenal gland
Anal canal, skin - A weak to moderate, mostly membranous MUC1 immunostaining is seen in this keratinizing squamous epithelium from the anal skin.
Aorta, media
Appendix, mucosa
Appendix, muscular wall
Bone marrow
Breast - A moderate to strong cytoplasmic MUC1 immunostaining with apical predominance is seen in breast glands. MUC1 staining may be weaker in basal cells.
Bronchus, mucosa - A variable, moderate to strong MUC1 staining occurs in respiratory epithelium.
Bronchus, mucosa - A variable, moderate to strong MUC1 staining occurs in respiratory epithelium.
Cerebellum (molecular layer, Purkinje cell layer, granule cell layer, white matter)
Cerebellum (white matter)
Cerebrum, grey matter - A weak fibrillar MUC1 staining can be seen in samples from the cerebrum.
Cerebrum, grey matter
Cerebrum, white matter - A weak fibrillar MUC1 staining can be seen in samples from the cerebrum.
Cerebrum, white matter
Colon descendens, mucosa
Colon descendens, muscular wall
Duodenum, Brunner gland - A weak apical membranous staining is occasionally seen in Brunner glands.
Duodenum, mucosa
Epididymis - In the epididymis the staining varies from strong diffuse cytoplasmic with apical predominance to only apical membranous staining. This sample shows a particularly strong staining.
Esophagus, squamous epithelium - A strong MUC1 immunostaining is seen in this non-keratinizing squamous epithelium of the esophagus.
Fallopian tube, mucosa - A strong cytoplasmic MUC1 immunostaining with apical predominance is seen in the epithelium of the fallopian tube.
Fat
Gallbladder, epithelium - A weak to moderate membranous MUC1 staining is seen in gallbladder epithelium.
Heart muscle
Ileum, mucosa
Kidney, cortex - Distal tubuli and collecting ducts show a strong cytoplasmic MUC1 staining while proximal tumuli are completely negative and cells of the Bowman’s capsule show weak to moderate positivity.
Kidney, medulla - A strong cytoplasmic MUC1 staining is seen in collecting ducts.
Liver - A weak to moderate, predominantly apical MUC1 staining is seen in intrahepatic bile ducts, while hepatocytes are negative.
Lung - In the lung, a strong MUC1 staining is seen in all pneumocytes.
Lymph node - Faint MUC1 staining of few cells in the germinal centre.
Ovary, stroma
Pancreas - Pancreatic acinar cells show a strong MUC1 immunostaining of the apical membranes and of granular (Golgi like) structures below the apical surface.
Parathyroid
Parotid gland - In salivary glands, a moderate MUC1 immunostaining of apical membranes of serous glandular cells and of excretory ducts is seen.
Peripheral nerves - Sheaths of peripheral nerves show moderate MUC1 staining.
Pituitary gland, anterior lobe - In the adenohypophysis a moderate staining with apical predominance is seen in a fraction of cells/acini.
Pituitary gland, posterior lobe - A strong fibrillar MUC1 staining occurs in the neurohypophsis.
Placenta (amnion and chorion) - A strong cytoplasmic staining is seen in amnion and chorion cells of the placenta.
Placenta, early - In the first trimenon, a predominantly membranous MUC1 staining can occur in a fraction of trophoblastic cells.
Placenta, early - In the first trimenon, a predominantly membranous MUC1 staining can occur in a fraction of trophoblast cells.
Placenta, early - A predominantly membranous MUC1 staining can occur in a fraction of trophoblast cells, especially in the first trimenon.
Placenta, mature - In the mature placenta, a predominantly membranous MUC1 staining can occur in a fraction of trophoblastic cells.
Placenta, mature - A predominantly membranous MUC1 staining can occur in a fraction of trophoblast cells. In this sample, the staining is strong.
Prostate - MUC1 immunostaining is variable in the prostate. In this sample, a weak MUC1 staining of luminal cells is seen in few glands while others are completely negative.
Prostate - MUC1 immunostaining is variable in the prostate. In this sample, a moderate to strong MUC1 staining of luminal and basal cells is seen in a fraction of cells of some glands.
Rectum, mucosa
Seminal vesicle - A strong apical MUC1 staining focally occurs in seminal vesicle epithelium.
Sinus paranasales - A variable, moderate to strong MUC1 staining occurs in respiratory epithelium.
Skeletal muscle
Skin - MUC1 immunostaining is usually absent in the skin.
Skin (sebaceous glands) - A strong MUC1 immunostaining is seen in sebaceous glands, while the skin is usually MUC1 negative.
Spleen
Stomach, antrum - Mucous producing glands of the stomach show variable, sometimes also strong MUC1 positivity while the surface epithelial cells of the stomach are largely MUC1 negative.
Stomach, corpus - Mucous producing glands of the stomach show a strong MUC1 positivity in this sample while the surface epithelial cells are largely MUC1 negative.
Testis
Thymus - Some elements of corpuscles of Hassall’s show a weak to moderate MUC1 staining.
Thyroid gland - A moderate apical MUC1 staining is seen in follicles, sometimes accompanied by a moderate to strong cytoplasmic staining.
Tonsil - A fraction of squamous epithelial cells of tonsil crypts show a moderate to strong MUC1 staining. Plasma cells are also MUC1 positive.
Tonsil, surface epithelium - A moderate to strong MUC1 immunostaining is seen in this non-keratinizing squamous epithelia of the tonsil surface. The staining is more prominent in the upper than in the basal layers
Urinary bladder, muscular wall
Urinary bladder, urothelium - A moderate to strong MUC1 immunostaining can be seen in the urothelium. The staining is most prominent in the umbrella cells.
Uterus, ectocervix - A very faint membranous MUC1 immunostaining is seen in this non-keratinizing squamous epithelium from the ectocervix.
Uterus, endocervix - A strong cytoplasmic MUC1 immunostaining with apical predominance is seen in the endocervical epithelium.
Uterus, endometrium (pregnancy) - A strong cytoplasmic MUC1 immunostaining with apical predominance is seen in the pregnant endometrium. Decidua cells are MUC1 negative.
Uterus, endometrium (proliferation) - A very strong MUC1 immunostaining is seen in the endometrium, where the stroma is also often MUC1 positive.
Uterus, endometrium (secretion) - A very strong MUC1 immunostaining is seen in the endometrium, where the stroma is also often MUC1 positive.
Uterus, myometrium