Adrenal gland- Adrenocortical adenoma with strong membranous CD56 staining of tumor cells
Adrenal gland- Adrenocortical adenoma with weak to moderate CD56 positivity of most tumor cells.
Adrenal gland- Pheochromocytoma with strong CD56 positivity of all tumor cells.
Breast- CD56 negative invasive breast cancer of no special type (NST).
Colon- CD56 negative colorectal adenocarcinoma.
Esophagus- CD56 negative adenocarcinoma.
Esophagus- CD56 negative squamous cell carcinoma.
Kidney- CD56 negative clear cell renal cell carcinoma.
Kidney- Clear cell carcinoma with strong CD56 immunostaining of about 60_ of tumor cells.
Larynx- CD56 negative squamous cell carcinoma
Liver- CD56 negative hepatocellular carcinoma
Lung- CD56 negative adenocarcinoma.
Lung- CD56 negative malignant mesothelioma (epitheloid)
Lung- Neuroendocrine tumor displaying a strong membranous CD56 staining of tumor cells.
Lung- Strong CD56 immunostaining of tumor cells in a small cell carcinoma
Lymph node- CD56 negative Hodgkin’s lymphoma. Only few non-neoplastic lymphocytes show CD56 positivity.
Ovary- CD56 negative Brenner tumor. Strong CD56 staining is only seen in the tumor stroma.
Ovary- Serous high-grade carcinoma showing intense membranous CD56 positivity of tumor cells.
Pancreas- CD56 negative ductal adenocarcinoma.
Pancreas- Neuroendocrine tumor with moderate CD56 positivity of few tumor cells.
Penis- CD56 negative squamous cell carcinoma.
Prostate- CD56 negative adenocarcinoma (Gleason 3+3=6)
Salivary gland- CD56 negative Warthin tumor.
Salivary gland- Pleomorphic adenoma with strong CD56 staining of most tumor cells.
Skin- CD56 negative malignant melanoma.
Skin- Merkel cell carcinoma showing a strong membranous CD56 positivity.
Soft tissue- CD56 negative liposarcoma.
Soft tissue- Granular cell tumor with moderate intensity membranous and cytoplasmic CD56 staining.
Soft tissue- Leiomyosarcoma with strong CD56 positivity of tumor cells.
Soft tissue- Liposarcoma with strong membranous CD56 staining of all tumor cells.
Soft tissue- Malignant peripheral nerve sheath tumor (MPNST) with strong CD56 immunostaining of tumor cells.
Soft tissue- Primitive neuroektodermal tumor (PNET) displaying a weak to moderate CD56 positivity of tumor cells.
Stomach- CD56 negative gastric adenocarcinoma.
Stomach- CD56 negative gastrointestinal stromal tumor (GIST).
Testis- CD56 negative seminoma.
Testis- Leydig cell tumor showing a moderate to strong cytoplasmic and membranous CD56 staining of tumor cells.
Thyroid- Follicular carcinoma with strong membranous CD56 positivity of tumor cells.
Thyroid- Medullary cancer with strong CD56 positivity of all tumor cells.
Urinary bladder- CD56 negative muscle-invasive urothelial carcinoma.
Uterus- Leiomyoma with strong CD56 immunostaining of tumor cells.