Brain Cerebrum Negative.
Cerebellum Negative.
Endocrine Tissues Thyroid Negative.
Parathyroid Negative.
Adrenal gland Negative.
Pituitary gland Negative.
Respiratory system Respiratory epithelium Negative.
Lung Negative.
Gastrointestinal Tract Salivary glands Negative.
Esophagus Negative.
Stomach Negative.
Colon Negative.
Duodenum Negative.
Rectum Negative.
Small intestine Negative.
Liver Negative.
Gallbladder Negative.
Pancreas Negative.
Genitourinary Kidney Negative.
Urothelium Negative.
Male genital Prostate Negative.
Seminal vesicles Negative.
Testis Negative.
Epididymis Negative.
Female genital Breast Negative.
Uterus, ectocervix Negative.
Uterus endocervix A weak PLAP staining can be seen at the surface apical membrane of epithelial cells (not in all samples).
Uterus, endometrium A weak PLAP staining can be seen at the surface apical membrane of epithelial cells (not in all samples).
Fallopian Tube A weak PLAP staining can be seen at the surface apical membrane of epithelial cells (not in all samples).
Ovary Negative.
Placenta early PLAP staining is only moderate and limited to the surface cell membrane of trophoblast cells.
Placenta mature Strong PLAP staining of the cytotrophoblast and the syncytiotrophoblast.
Amnion Weak PLAP staining of amnion cells.
Chorion Strong PLAP staining of chorion cells.
Skin Epidermis Negative.
Sebaceous glands Negative.
Muscle/connective tissue Heart Negative.
Skeletal Negative.
Smooth muscle Negative.
Fat Negative.
Bone marrow/lymphoid Bone marrow Negative.
Lymph node Negative.
Spleen Negative.
Thymus Negative.
Tonsil Negative.
Remarks

 

These findings are highly consistent with the RNA and protein data described in the Human Protein Atlas (Tissue expression PLAP). The protein atlas data also suggest the uterus as an alternative source of limited PLAP expression besides placenta. That lung was also described in the protein atlas as a source of very limited PLAP RNA amounts cannot be explained by findings in this analysis.

 

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