Adrenal gland – Weak TLE1 staining of a fraction of adrenocortical cells
Aorta, media – Moderate TLE1 positivity of a subset of spindle cells in the media
Appendix, mucosa – Weak to moderate TLE1 staining in epithelial cells. In this sample, staining is most intense at the surface and weaker in the crypts
Appendix, muscular wall – Weak to moderate TLE1 positivity of smooth muscle cells, strong positivity of at least a fraction of neuronal cells
Bone marrow – Weak to strong TLE1 positivity of a significant fraction of cells-1
Breast – Moderate TLE1 staining of luminal epithelial cells. Staining of basal-myoepithelial cells is much less intense or absent
Bronchus, mucosa – Weak to moderate TLE1 staining of a small subset of (non-basal) epithelial cells
Cerebrum, grey matter – Weak to moderate TLE1 staining of subsets of glial and neuronal cells
Cerebrum, white matter – Weak to moderate TLE1 staining of subsets of glial cells
Colon descendens, mucosa – Weak to moderate TLE1 staining in epithelial cells. Staining is stronger in crypts than at the surface
Colon descendens, muscular wall
Duodenum, Brunner gland – Weak to moderate staining of Brunner glands
Duodenum, mucosa – Some staining can occur in epithelial cells. Staining is stronger in crypts than in villi
Epididymis – Moderate to strong TLE1 staining in non-basal epithelial cells
Esophagus, squamous epithelium – Weak TLE1 staining of a subset of lymphocytes and of the squamous epithelium, predominantly of the suprabasal cell layers
Fallopian tube, mucosa – Moderate TLE1 staining of stromal cells and of a fraction of epithelial cells
Fat
Gallbladder, epithelium – Moderate TLE1 staining of epithelial cells
Heart muscle
Ileum, mucosa – Some staining can occur in epithelial cells. Staining is stronger in crypts than in villi
Kidney, cortex – Significant TLE1 staining can occur in altered tubuli such as in atrophy
Kidney, cortex – Weak to moderate staining of few glomerular cells and of cells of parietal layer of the Bowman capsule. Staining is often faint or absent in tubular cells
Kidney, medulla – TLE1 staining is often faint or absent in tubular and collecting duct cells
Liver – Weak to moderate TLE1 staining of bile duct cells. Faint staining of hepatocytes
Lung – Weak to moderate TLE1 staining of mostly vascular cells
Lymph node – Weak to moderate TLE1 staining in a subset of lymphocytes, predominantly in germinal centres
Ovary, corpus luteum – TLE1 staining of corpus luteum cells is only faint
Ovary, follicular cyst – Strong TLE1 staining of theca interna cells while staining for granulosa cells is only faint
Ovary, stroma – Ovarian stroma is largely TLE1 negative (except endothelial cells)
Pancreas – Weak to moderate TLE1 staining of acinar and ductal cells
Pancreas – Weak to moderate TLE1 staining of acinar cells and of most islet cells
Parathyroid gland – TLE1 staining is largely limited to endothelial cells
Parotid gland – Moderate to strong TLE1 staining of serous glandular cells. Staining is weaker in mucinous cells and largely absent in excretory ducts
Pituitary gland, anterior lobe – Weak to moderate TLE1 staining of a fraction of epithelial cells
Pituitary gland, posterior lobe
Placenta (amnion and chorion) – Intense TLE1 positivity of amnion cells
Placenta (amnion and chorion) – Strong TLE1 staining of amnion and chorion cells
Placenta, early – Moderate to strong TLE1 staining of trophoblast and some stroma cells
Placenta, mature – TLE1 staining is weak to moderate in some stroma cells and in trophoblast cells
Prostate – Weak to moderate TLE1 staining in acinar cells. Staining is weak or absent in basal cells
Rectum, mucosa – Weak to moderate TLE1 staining in epithelial cells. Staining is stronger in crypts than at the surface
Seminal vesicle – TLE1 staining of variable intensity in a subset of epithelial cells
Sinus paranasales – Weak to moderate TLE1 staining of a large subset of (non-basal) epithelial cells
Skeletal muscle – Moderate to strong TLE1 positivity of skeletal muscle cells
Skin, hair follicel and sebaceous glands – Moderate to strong TLE1 positivity of sebaceous and of squamous cells
Spleen – Moderate to strong TLE1 staining of sinus endothelial cells. Weak to moderate TLE1 staining in a subset of lymphocytes
Stomach, antrum – Weak to moderate TLE1 staining in epithelial cells. Staining is somewhat stronger in the surface epithelium than in glands
Stomach, corpus – Weak to moderate TLE1 staining in epithelial cells. Staining is somewhat stronger in the surface epithelium than in glands
Testis – Moderate to strong TLE1 staining of spermatogonia
Thymus – Weak to moderate TLE1 staining of a subset of cells of corpuscles of Hassall’s and of few other cells
Thyroid gland – Weak TLE1 staining of follicular and endothelial cells
Tonsil – Weak to moderate TLE1 staining in a subset of lymphocytes, predominantly in germinal centres. Moderate TLE1 staining of a major subset of crypt epithelial cells
Tonsil, surface epithelium – Weak to moderate TLE1 staining of a subset of lymphocytes and of the squamous epithelium, predominantly of the suprabasal cell layers
Tonsil, surface epithelium
Urinary bladder, muscular wall
Urinary bladder, urothelium – Weak TLE1 staining of urothelial cells (somewhat more in upper cell layers)_
Uterus, ectocervix – Moderate TLE1 staining of squamous epithelial cells, predominantly of the suprabasal cell layers
Uterus, endocervix – Weak to moderate TLE1 staining of epithelial, stromal, and endothelial cells
Uterus, endometrium (pregnancy) – Strong TLE1 staining of decidua cells
Uterus, endometrium (proliferation) – Moderate to strong TLE1 staining of epithelial and stromal cells
Uterus, endometrium (secretion) – Moderate to strong TLE1 staining of most epithelial cells
Uterus, myometrium – Weak to moderate TLE1 positivity of smooth muscle cells