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Normal Tissue Gallery SOX9

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Adrenal gland – Few interspersed cells in the cortex showing weak to moderate SOX9 positivity
Adrenal gland - Few interspersed cells in the cortex showing weak to moderate SOX9 positivity
Aorta, media
Aorta, media
Appendix, mucosa – Strong nuclear SOX9 staining of crypt epithelial cells, especially at the base. SOX9 staining intensity gradually decreases towards the surface. The surface epithelium remains SOX9 negative (or shows only a very weak staining).
Appendix, mucosa - Strong nuclear SOX9 staining of crypt epithelial cells, especially at the base. SOX9 staining intensity gradually decreases towards the surface. The surface epithelium remains SOX9 negative (or shows only a very weak staining).
Appendix, muscular wall
Appendix, muscular wall
Bone marrow
Bone marrow
Breast – Epithelial cells are largely SOX9 negative or may show faint staining
Breast - Epithelial cells are largely SOX9 negative or may show faint staining
Bronchus, mucosa – Moderate to strong SOX9 positivity of most epithelial cells
Bronchus, mucosa - Moderate to strong SOX9 positivity of most epithelial cells
Cerebellum, cortex (Stratum moleculare) – 2
Cerebellum, cortex (Stratum moleculare) - 2
Cerebellum, cortex (Stratum moleculare)
Cerebellum, cortex (Stratum moleculare)
Cerebrum, grey
Cerebrum, grey
Cerebrum, white
Cerebrum, white
Colon descendens, mucosa – Strong nuclear SOX9 staining of crypt epithelial cells, especially at the base. SOX9 staining intensity gradually decreases towards the surface. The surface epithelium remains SOX9 negative (or shows only a very weak staining).
Colon descendens, mucosa - Strong nuclear SOX9 staining of crypt epithelial cells, especially at the base. SOX9 staining intensity gradually decreases towards the surface. The surface epithelium remains SOX9 negative (or shows only a very weak staining).
Colon descendens, muscular wall
Colon descendens, muscular wall
Duodenum, Brunner gland – Strong SOX9 staining of Brunner gland cells
Duodenum, Brunner gland - Strong SOX9 staining of Brunner gland cells
Duodenum, mucosa – Strong nuclear SOX9 staining of crypt epithelial cells. The SOX9 staining intensity markedly decreases towards the surface epithelium and the tips of the villosities remain SOX9 negative.
Duodenum, mucosa - Strong nuclear SOX9 staining of crypt epithelial cells. The SOX9 staining intensity markedly decreases towards the surface epithelium and the tips of the villosities remain SOX9 negative.
Endometrium, secretion – Strong SOX9 positivity of epithelial cells. Stroma cells are SOX9 negative
Endometrium, secretion - Strong SOX9 positivity of epithelial cells. Stroma cells are SOX9 negative
Epididymis – Weak to moderate nuclear SOX9 staining of basal cells in the caput
Epididymis - Weak to moderate nuclear SOX9 staining of basal cells in the caput
Esophagus, squamous epithelium – Weak to moderate nuclear SOX9 staining of the bottom 2-3 of squamous epithelium
Esophagus, squamous epithelium - Weak to moderate nuclear SOX9 staining of the bottom 2-3 of squamous epithelium
Fallopian tube, mucosa – Moderate to strong SOX9 staining of a large subset of epithelial cells
Fallopian tube, mucosa - Moderate to strong SOX9 staining of a large subset of epithelial cells
Fat
Fat
Gallbladder, epithelium
Gallbladder, epithelium
Heart
Heart
Ileum, mucosa – Strong nuclear SOX9 staining of crypt epithelial cells, especially at the base. SOX9 staining intensity gradually decreases towards the surface. The surface epithelium remains SOX9 negative (or shows only a very weak staining).
Ileum, mucosa - Strong nuclear SOX9 staining of crypt epithelial cells, especially at the base. SOX9 staining intensity gradually decreases towards the surface. The surface epithelium remains SOX9 negative (or shows only a very weak staining).
Kidney, cortex – Few cells of the tubuli may show a weak to moderate SOX9 staining
Kidney, cortex - Few cells of the tubuli may show a weak to moderate SOX9 staining
Kidney, medulla – Moderate to strong SOX9 staining of a subset of collecting duct cells
Kidney, medulla - Moderate to strong SOX9 staining of a subset of collecting duct cells
Liver – Moderate to strong nuclear SOX9 staining of intrahepatic bile ducts
Liver - Moderate to strong nuclear SOX9 staining of intrahepatic bile ducts
Lung
Lung
Lymph node – Weak to moderate nuclear SOX9 positivity of a fraction of cells in germinal centres
Lymph node - Weak to moderate nuclear SOX9 positivity of a fraction of cells in germinal centres
Ovary, stroma
Ovary, stroma
Pancreas – Strong nuclear SOX9 staining of intercalated and excretory ducts, while acinar cells are less often positive and islet cells are SOX9 negative
Pancreas - Strong nuclear SOX9 staining of intercalated and excretory ducts, while acinar cells are less often positive and islet cells are SOX9 negative
Parathyroid
Parathyroid
Parotid gland – Moderate to strong nuclear SOX9 staining of all epithelial cell types
Parotid gland - Moderate to strong nuclear SOX9 staining of all epithelial cell types
Pituitary, anterior lobe – Moderate to strong SOX9 staining of a small subset of epithelial cells in the adenohypophysis
Pituitary, anterior lobe - Moderate to strong SOX9 staining of a small subset of epithelial cells in the adenohypophysis
Pituitary, anterior lobe – Weak to moderate SOX9 positivity of fibrillar cells in the neurohypophysis
Pituitary, anterior lobe - Weak to moderate SOX9 positivity of fibrillar cells in the neurohypophysis
Placenta early, decidua
Placenta early, decidua
Placenta, early
Placenta, early
Placenta, mature
Placenta, mature
Placenta, mature, amnion and chorion
Placenta, mature, amnion and chorion
Placenta, mature, amnion and chorion (2)
Placenta, mature, amnion and chorion (2)
Prostate – Strong SOX9 positivity of basal cells while luminal cells show only a markedly weaker staining
Prostate - Strong SOX9 positivity of basal cells while luminal cells show only a markedly weaker staining
Rectum, mucosa – Strong nuclear SOX9 staining of crypt epithelial cells, especially at the base. SOX9 staining intensity gradually decreases towards the surface. The surface epithelium remains SOX9 negative (or shows only a very weak staining).
Rectum, mucosa - Strong nuclear SOX9 staining of crypt epithelial cells, especially at the base. SOX9 staining intensity gradually decreases towards the surface. The surface epithelium remains SOX9 negative (or shows only a very weak staining).
Seminal vesicle – Moderate to strong SOX9 positivity of epithelial cells
Seminal vesicle - Moderate to strong SOX9 positivity of epithelial cells
Sinus paranasales – Moderate to strong SOX9 positivity of most epithelial cells
Sinus paranasales - Moderate to strong SOX9 positivity of most epithelial cells
Skin – Weak to moderate nuclear SOX9 staining of the bottom 2-3 of squamous epithelium
Skin – Weak to moderate nuclear SOX9 staining of the bottom 2-3 of squamous epithelium
Skin (sebaceous and ekkrine glands) – Strong SOX9 staining of ekkrine glands. Weak to moderate nuclear SOX9 staining of sebaceous glands
Skin (sebaceous and ekkrine glands) - Strong SOX9 staining of ekkrine glands. Weak to moderate nuclear SOX9 staining of sebaceous glands
Spleen
Spleen
Stomach, antrum – Moderate to strong nuclear SOX9 staining of surface epithelial cells, while the glandular cells are SOX9 negative
Stomach, antrum - Moderate to strong nuclear SOX9 staining of surface epithelial cells, while the glandular cells are SOX9 negative
Stomach, corpus – Moderate to strong nuclear SOX9 staining of surface epithelial cells, while the glandular cells only show weak positivity
Stomach, corpus - Moderate to strong nuclear SOX9 staining of surface epithelial cells, while the glandular cells only show weak positivity
Striated muscle
Striated muscle
Sublingual gland – Moderate to strong nuclear SOX9 staining of all epithelial cell types
Sublingual gland - Moderate to strong nuclear SOX9 staining of all epithelial cell types
Testis – Strong SOX9 staining of Sertoli cells
Testis - Strong SOX9 staining of Sertoli cells
Thymus
Thymus
Thyroid gland – Moderate to strong SOX9 positivity of follicular cells
Thyroid gland - Moderate to strong SOX9 positivity of follicular cells
Tonsil – Weak to moderate nuclear SOX9 positivity of a fraction of cells in germinal centres and in a fraction of krypt epithelial cells
Tonsil - Weak to moderate nuclear SOX9 positivity of a fraction of cells in germinal centres and in a fraction of krypt epithelial cells
Tonsil, surface epithelium – Faint nuclear SOX9 staining of some epithelial cells, mainly in the bottom 2-3 of the squamous epithelium
Tonsil, surface epithelium - Faint nuclear SOX9 staining of some epithelial cells, mainly in the bottom 2-3 of the squamous epithelium
Urinary bladder, muscular wall
Urinary bladder, muscular wall
Urinary bladder, urothelium – A weak SOX9 staining can occur in the superficial cell layers (umbrella cells) of the urothelium
Urinary bladder, urothelium - A weak SOX9 staining can occur in the superficial cell layers (umbrella cells) of the urothelium
Uterus, ectocervix – Weak to moderate nuclear SOX9 staining of the bottom 2-3 of squamous epithelium
Uterus, ectocervix - Weak to moderate nuclear SOX9 staining of the bottom 2-3 of squamous epithelium
Uterus, endocervix – Weak nuclear SOX9 staining of epithelial cells
Uterus, endocervix - Weak nuclear SOX9 staining of epithelial cells
Uterus, endometrium (proliferation) – Moderate SOX9 positivity of epithelial cells. Stroma cells are SOX9 negative
Uterus, endometrium (proliferation) - Moderate SOX9 positivity of epithelial cells. Stroma cells are SOX9 negative
Uterus, myometrium
Uterus, myometrium
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