Normal Tissue Gallery PAX8

Adrenal gland – Complete lack of PAX8 staining

Aorta, media

Appendix, mucosa

Appendix, muscular wall

Bone marrow

Breast

Bronchus, mucosa

Cerebellum (molecular layer, Purkinje cell layer, granule cell layer)

Cerebellum (white matter)

Cerebrum, grey matter

Cerebrum, white matter

Colon descendens, mucosa

Colon descendens, muscular wall

Duodenum, Brunner gland

Duodenum, mucosa

Epididymis – Strong nuclear PAX8 staining of epithelial cells in the cauda epididymis

Epididymis – Variable, weak to strong nuclear PAX8 staining of epithelial cells in the cauda epididymis

Esophagus, squamous epithelium

Fallopian tube, mucosa – Strong PAX8 staining of a subset of epithelial cells of the fallopian tube

Fat

Gallbladder, epithelium – A faint (non-specific) and purely cytoplasmic PAX8 staining can occur in stomach glands

Heart muscle

Ileum, mucosa

Kidney, cortex – Variable, weak to strong nuclear PAX8 staining of cells of proximal and distal tubuli as well as of parietal epithelial cells of the Bowman’s capsule

Kidney, medulla – Variable, weak to strong nuclear PAX8 staining of epithelial cells of the collecting ducts

Kidney, pelvis, urothelium – A weak to moderate PAX8 staining can occur in basal and suprabasal cell layers of the urothelium of the kidney pelvis

Liver

Lung

Lymph node

Ovary, corpus luteum

Ovary, follicular cyst

Ovary, stroma

Pancreas – Absence of PAX8 staining in acinar and islet cells

Pancreas – Complete lack of PAX8 staining in acinar and in islet cells

Parathyroid gland – Complete lack of PAX8 staining

Parotid gland

Pituitary gland, anterior lobe – A weak to moderate (non-specific) and purely cytoplasmic PAX8 staining can occur in a fraction of epithelial cells

Pituitary gland, anterior lobe

Pituitary gland, posterior lobe

Placenta (amnion and chorion)

Placenta, early

Placenta, mature

Prostate

Prostate (2)

Rectum, mucosa

Skeletal muscle

Skin

Skin, hairfollicel and sebaceous glands

Spleen

Stomach, antrum

Stomach, corpus – A faint (non-specific) and purely cytoplasmic PAX8 staining can occur in stomach glands

Stomach, corpus

Testis

Thymus

Thyroid gland – Strong, predominantly nuclear PAX8 staining of all epithelial cells

Tonsil, surface epithelium

Tonsil

Urinary bladder, muscular wall

Urinary bladder, urothelium – PAX8 staining is usually completely absent in urothelium of the urinary bladder

Urinary bladder, urothelium – PAX8 staining is usually lacking in urothelium of the bladder

Uterus, ectocervix

Uterus, endocervix – Strong nuclear PAX8 staining of all epithelial cells

Uterus, endometrium (pregnancy) – Strong PAX8 staining of endometrium cells while stroma and decidua cells remain negative

Uterus, endometrium (proliferation) – Strong nuclear PAX8 staining of all endometrium cells. Stroma cells are always negative

Uterus, endometrium (proliferation) – Variable, weak to strong nuclear PAX8 staining of endometrium cells

Uterus, endometrium (secretion) – Weak to moderate PAX8 staining of most endometrium cells

Uterus, endometrium (secretion) – Strong nuclear PAX8 staining of all endometrium cells

Uterus, myometrium