Normal Tissue Gallery IgA (Immunglobulin Alpha Heavy Chain)

Adrenal gland

Aorta, media

Appendix, mucosa – IgA positive plasma cells are numerous in the stroma. IgA also accumulates in the cytoplasm of the crypt epithelium.

Appendix, muscular wall

Bone marrow – IgA positive plasma cells are rather rare.

Breast – IgA positive secreted liquid is seen in breast glands in this sample.

Breast – IgA staining is lacking in this sample.

Bronchus, mucosa

Cerebellum, cortex (Stratum moleculare)

Cerebellum, grey (Stratum neuronorum)

Cerebrum, grey matter

Cerebrum, white matter

Colon descendens, mucosa

Colon descendens, muscular wall

Duodenum, Brunner gland

Duodenum, mucosa – IgA positive plasma cells are abundant in the stroma.

Epididymis – IgA positive plasma cells are lacking in the epididymis but some IgA staining occurs in blood serum.

Esophagus, squamous epithelium – Few IgA positive plasma cells are seen.

Fallopian tube, mucosa

Fat

Gallbladder, epithelium

Heart muscle

Ileum, mucosa – Numerous IgA positive plasma cells in the stroma

Kidney, cortex

Kidney, medulla

Liver

Lung

Lymph node – A fraction of plasma cells are IgA positive.

Ovary, stroma

Pancreas

Parathyroid gland

Parotid gland

Pituitary gland, anterior lobe – Some IgA staining can occurs in the adenohypophysis.

Pituitary gland, anterior lobe

Pituitary gland, posterior lobe

Placenta (amnion and chorion) – Stromal IgA staining is occasionally seen – probably caused by IgA from the blood.

Placenta (amnion and chorion)

Placenta, early – Some IgA staining occurs in the cytotrophoblast.

Placenta, mature

Prostate

Seminal vesicle

Sinus paranasales – Abundance of IgA positive plasma cells.

Skeletal muscle

Skin

Spleen – Few IgA positive plasma cells are seen

Stomach, antrum – Few IgA positive plasma cells are seen.

Stomach, antrum – IgA positive plasma cells are occur in the stroma. IgA also accumulates in the cytoplasm of superficial epitheial cell layers.

Stomach, corpus – IgA positive plasma cells are abundant in the stroma. IgA also accumulates in the cytoplasm of superficial epitheial cell layers.

Testis

Testis

Thymus – Few IgA positive plasma cells are seen.

Thyroid gland – Some IgA staining can occurs in the colloid of some follicles

Tonsil – Numerous IgA positive plasma cells are seen. Week staining is also seen in the crypts as a result of IgA secretion

Tonsil, surface epithelium – IgA positive plasma cells are abundant.

Urinary bladder, muscular wall

Urinary bladder, urothelium – IgA positive plasma cells are abundant in the stroma. IgA accumulates in the superficial layers of the urothelium.

Urinary bladder, urothelium – IgA positive plasma cells are abundant in this sample. A faint IgA staining also occurs in the superficial urothelial cell layer.

Uterus, ectocervix

Uterus, endocervix

Uterus, endometrium (pregnancy)

Uterus, endometrium (secretion)

Uterus, myometrium