Normal Tissue Gallery Cytokeratin 17

Adrenal gland

Anal canal, skin

Aorta, media

Appendix, muscular wall

Breast – CK17 staining of basal-myoepithelial cells is more prominent in excretory ducts than in small glands

Bronchus, glands – Basal cells of the respiratory epithelium and myoepithelial cells of bronchial glands are CK17 positive

Bronchus, mucosa – Basal cells of the respiratory epithelium exhibit strong CK17 staining

Cerebellum (molecular layer, Purkinje cell layer, granule cell layer, white matter)

Cerebellum (molecular layer, Purkinje cell layer, granule cell layer)

Cerebellum (white matter)

Cerebrum, grey matter

Cerebrum, white matter

Colon descendens, muscular wall

Colon, mucosa

Duodenum, Brunner gland

Duodenum, mucosa

Epididymis – Basal cells in the caput epididymis exhibit strong CK17 staining

Esophagus, squamous epithelium – Faint CK17 staining of basal cells in this sample of squamous epithelium of the esophagus

Esophagus, squamous epithelium

Fallopian tube, mucosa

Fat

Gallbladder, epithelium

Heart muscle

Ileum, mucosa

Kidney, cortex

Kidney, medulla – Absence of CK17 staining in this sample

Kidney, medulla – Strong CK17 positivity of a subset of tubular cells in a subset of samples

Liver

Liver

Lung

Lymph node

Ovary, stroma

Pancreas – Strong CK17 staining of a subset of small excretory ducts while intercalated ducts and large excretory ducts are CK17 negative

Pancreas

Parathyroid gland

Parotid gland – Strong CK17 positivity of basal cells of excretory ducts and of myoepithelial cells. Glandular cells are not stained

Pituitary gland, anterior lobe

Pituitary gland, posterior lobe

Placenta (amnion and chorion) – Strong CK17 staining of amnion cells while the staining of chorion cells is somewhat less intense but still strong

Placenta, early

Placenta, mature

Prostate – Basal cells show strong CK17 positivity

Rectum, mucosa

Seminal vesicle – CK17 staining of at least a subset of basal cells

Sinus paranasales – CK17 staining predominates in the basal cell layers

Skeletal muscle

Skin, hairfollicel and sebaceous glands – Strong CK17 staining of hair follicles and of sebaceous glands

Spleen

Stomach, antrum

Stomach, corpus

Sublingual gland – Strong CK17 staining of myoepithelial cells

Submandibular gland – Strong CK17 staining of basal cells of excretory ducts and of myoepithelial cells. Glandular cells are not stained_

Submandibular gland – Strong CK17 staining of basal cells of excretory ducts and of myoepithelial cells. Glandular cells are not stained

Testis

Thymus – A large subset of thymic epithelial cells (including corpuscles of Hassall’s) show significant CK17 staining. Lymphocytes are negative

Thymus – CK17 positivity of a large subset of thymic epithelial cells

Tonsil – Strong CK17 staining of basal and suprabasal cells of crypt squamous epithelium

Tonsil, surface epithelium

Thyroid gland

Urinary bladder, muscular wall

Urinary bladder, urothelium – Strong CK17 staining of basal cells while staining is much less intense in the upper cell layers of the urothelium

Uterus, ectocervix

Uterus, endocervix – CK17 positive basal cells are lacking in this sample

Uterus, endocervix – Strong CK17 staining of few basal cells

Uterus, endometrium (pregnancy)

Uterus, endometrium (secretion)

Uterus, myometrium