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Normal Tissue Gallery AGR2
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Adrenal gland
Adrenal gland
Aorta, endothelium
Aorta, endothelium
Appendix, mucosa – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Appendix, mucosa – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Appendix, muscular wall
Appendix, muscular wall
Bone marrow
Bone marrow
Breast – Strong, predominantly cytoplasmic AGR2 staining of a subset of luminal cells
Breast – Strong, predominantly cytoplasmic AGR2 staining of a subset of luminal cells
Bronchus, mucosa – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Bronchus, mucosa – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Cerebellum (white matter)
Cerebellum (white matter)
Cerebellum, cortex (molecular layer, Purkinje cell layer, granule cell layer)
Cerebellum, cortex (molecular layer, Purkinje cell layer, granule cell layer)
Cerebrum, grey matter
Cerebrum, grey matter
Cerebrum, white matter
Cerebrum, white matter
Colon descendens, mucosa – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Colon descendens, mucosa – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Colon descendens, muscular wall
Colon descendens, muscular wall
Duodenum, Brunner gland – Moderate to strong, predominantly cytoplasmic AGR2 staining of Brunner gland cells. Strong AGR2 staining of duodenal epithelial cells
Duodenum, Brunner gland – Moderate to strong, predominantly cytoplasmic AGR2 staining of Brunner gland cells. Strong AGR2 staining of duodenal epithelial cells
Duodenum, mucosa – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Duodenum, mucosa – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Epididymis (Cauda) – Strong, predominantly cytoplasmic AGR2 staining of a subset of epithelial cells
Epididymis (Cauda) – Strong, predominantly cytoplasmic AGR2 staining of a subset of epithelial cells
Esophagus, squamous epithelium
Esophagus, squamous epithelium
Fallopian tube, mucosa
Fallopian tube, mucosa
Fat
Fat
Gallbladder, epithelium – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Gallbladder, epithelium – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Heart muscle
Heart muscle
Ileum, mucosa – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Ileum, mucosa – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Kidney, cortex – Moderate to strong predominantly cytoplasmic AGR2 staining of a small subset of tubuli-collecting ducts
Kidney, cortex – Moderate to strong predominantly cytoplasmic AGR2 staining of a small subset of tubuli-collecting ducts
Kidney, medulla – Lack of AGR2 staining in this sample
Kidney, medulla – Lack of AGR2 staining in this sample
Kidney, medulla – Moderate to strong predominantly cytoplasmic AGR2 staining of a small subset of tubuli-collecting ducts
Kidney, medulla – Moderate to strong predominantly cytoplasmic AGR2 staining of a small subset of tubuli-collecting ducts
Kidney, pelvis, urothelium – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Kidney, pelvis, urothelium – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Liver
Liver
Lung – Strong, predominantly cytoplasmic AGR2 staining of a large subset of pneumocytes
Lung – Strong, predominantly cytoplasmic AGR2 staining of a large subset of pneumocytes
Lymph node
Lymph node
Ovary, corpus luteum
Ovary, corpus luteum
Ovary, stroma
Ovary, stroma
Pancreas – In this sample, a strong, predominantly cytoplasmic AGR2 staining is seen in numerous individual or groups of acinar cells
Pancreas – In this sample, a strong, predominantly cytoplasmic AGR2 staining is seen in numerous individual or groups of acinar cells
Pancreas – Moderate to strong, predominantly cytoplasmic AGR2staining of intercalated duct cells. Islet cells are AGR2 negative
Pancreas – Moderate to strong, predominantly cytoplasmic AGR2staining of intercalated duct cells. Islet cells are AGR2 negative
Parathyroid gland
Parathyroid gland
Parotid gland
Parotid gland
Pituitary gland, anterior lobe – Predominantly cytoplasmic AGR2 staining of variable intensity in a large subset of epithelial cells
Pituitary gland, anterior lobe – Predominantly cytoplasmic AGR2 staining of variable intensity in a large subset of epithelial cells
Pituitary gland, anterior lobe – Predominantly cytoplasmic AGR2 staining of variable intensity in a subset of epithelial cells
Pituitary gland, anterior lobe – Predominantly cytoplasmic AGR2 staining of variable intensity in a subset of epithelial cells
Pituitary gland, posterior lobe
Pituitary gland, posterior lobe
Placenta (amnion and chorion)
Placenta (amnion and chorion)
Placenta, early
Placenta, early
Placenta, mature
Placenta, mature
Prostate – Complete absence of AGR2 staining in this sample
Prostate – Complete absence of AGR2 staining in this sample
Prostate – Strong, predominantly cytoplasmic AGR2 staining of all acinar and basal cells in this sample
Prostate – Strong, predominantly cytoplasmic AGR2 staining of all acinar and basal cells in this sample
Prostate – Strong, predominantly cytoplasmic AGR2 staining of few acinar and basal cells
Prostate – Strong, predominantly cytoplasmic AGR2 staining of few acinar and basal cells
Rectum, mucosa – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Rectum, mucosa – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Seminal vesicle
Seminal vesicle
Sinus paranasales – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Sinus paranasales – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Skeletal muscle
Skeletal muscle
Skin, hairfollicel and sebaceous glands – Strong cytoplasmic AGR2 staining of the inner (Huxley) layers of a hair follicle
Skin, hairfollicel and sebaceous glands – Strong cytoplasmic AGR2 staining of the inner (Huxley) layers of a hair follicle
Skin
Skin
Spleen
Spleen
Stomach, antrum – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Stomach, antrum – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Stomach, corpus – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells except parietal cells which only show a faint staining
Stomach, corpus – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells except parietal cells which only show a faint staining
Sublingual gland – Strong, predominantly cytoplasmic AGR2 staining of subset of mucinous glandular cells. Weak to moderate AGR2 staining of a subset of excretory duct cells
Sublingual gland – Strong, predominantly cytoplasmic AGR2 staining of subset of mucinous glandular cells. Weak to moderate AGR2 staining of a subset of excretory duct cells
Submandibular gland – Moderate to strong, predominantly cytoplasmic AGR2 staining of subset of glandular cells (especially mucinous)
Submandibular gland – Moderate to strong, predominantly cytoplasmic AGR2 staining of subset of glandular cells (especially mucinous)
Testis
Testis
Thymus – Strong cytoplasmic AGR2 staining of a fraction of (squamous) epithelial cells associated with a corpuscle of Hassall’s
Thymus – Strong cytoplasmic AGR2 staining of a fraction of (squamous) epithelial cells associated with a corpuscle of Hassall’s
Thyroid gland
Thyroid gland
Tonsil – Strong cytoplasmic AGR2 staining of a subset of squamous epithelial cells of tonsil crypts
Tonsil – Strong cytoplasmic AGR2 staining of a subset of squamous epithelial cells of tonsil crypts
Tonsil, surface epithelium
Tonsil, surface epithelium
Urinary bladder, muscular wall
Urinary bladder, muscular wall
Urinary bladder, urothelium – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells. Staining intensity is lowest in umbrella cells
Urinary bladder, urothelium – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells. Staining intensity is lowest in umbrella cells
Uterus, ectocervix
Uterus, ectocervix
Uterus, endocervix – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Uterus, endocervix – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Uterus, endometrium (pregnancy)
Uterus, endometrium (pregnancy)
Uterus, endometrium (proliferation) – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Uterus, endometrium (proliferation) – Strong, predominantly cytoplasmic AGR2 staining of all epithelial cells
Uterus, endometrium (secretion) – Strong, predominantly cytoplasmic AGR2 staining of virtually all epithelial cells
Uterus, endometrium (secretion) – Strong, predominantly cytoplasmic AGR2 staining of virtually all epithelial cells
Uterus, myometrium
Uterus, myometrium