Adrenal gland – Adrenocortical adenoma with faint membranous occludin immunostaining of most tumor cells
Adrenal gland – Occludin negative adrenocortical adenoma
Anal canal – Squamous cell carcinoma with moderate to strong occludin staining of tumor cells
Breast – Invasive breast cancer of no special type (NST) with strong, predominantly membranous occludin staining of tumor cells
Breast – Invasive lobular breast cancer with faint occludin staining of tumor cells
Colon– Colorectal adenocarcinoma with prominent occludin staining of the apical membrane of tumor cells
Esophagus – Adenocarcinoma with strong occludin staining of most tumor cells
Esophagus – Occludin negative squamous cell carcinoma
Kidney – Occludin negative clear cell carcinoma
Kidney – Oncocytoma with strong membranous occludin positivity of tumor cells
Kidney – Papillary renal cell carcinoma with strong membranous occludin staining of tumor cells
Liver – Cholangiocellular carcinoma with strong, predominantly membranous occluding positivity of most tumor cells
Liver – Hepatocellular carcinoma with faint occludin immunostaining of a subset of tumor cells
Liver – Hepatocellular carcinoma with moderate to strong occludin staining of tumor cells
Lung – Adenocarcinoma with strong occludin staining of all tumor cells
Lung – Occludin negative squamous cell carcinoma. Distinct occluding staining of endothelial cells of tumor associated blood vessels
Lymph node – Diffuse large B-cell lymphoma with weak occludin staining of a fraction of tumor cells
Lymph node – Hodgkin’s lymphoma with distinct occludin positivity of tumor cells
Lymph node – Hodgkin’s lymphoma with strong occludin positivity of tumor cells
Lymph node – Occludin negative diffuse large B-cell lymphoma
Ovary – Clear cell carcinoma with moderate occludin staining of tumor cells
Ovary – Serous high-grade carcinoma with strong membranous and cytoplasmic occludin staining of tumor cells
Pancreas – Acinar cell carcinoma with strong membranous and cytoplasmic occludin staining of tumor cells
Pancreas – Neuroendocrine tumor with strong occludin positivity of tumor cells
Penis – Occludin negative squamous cell carcinoma
Prostate – Adenocarcinoma (Gleason 3+3=6) with faint occludin staining of some tumor cells
Prostate – Adenocarcinoma (Gleason 5+5=10) with intense membranous and cytoplasmic occludin staining of tumor cells
Salivary gland – Warthin tumor with strong Occludin immunostaining of most tumor cells. Note- Staining is absent or faint in basal cell layers
Skin – Occludin negative malignant melanoma
Skin – Occludin negative squamous cell carcinoma
Soft tissue –Leiomyosarcoma with weak to moderate occludin staining of tumor cells
Stomach – Gastric adenocarcinoma (diffuse type) with moderate occludin immunostaining of all cells
Stomach – Gastric adenocarcinoma (intestinal type) with moderate to strong occludin staining of all tumor cells
Testis – Leydig cell tumor with strong occludin positivity of tumor cells
Testis – Seminoma with weak to moderate occludin immunostaining of most tumor cells
Thyroid – Medullary cancer with moderate to strong occludin staining of tumor cells
Thyroid – Papillary cancer with weak to moderate occludin staining of most tumor cells
Urinary bladder – Muscle-invasive urothelial carcinoma with strong, predominantly membranous occludin staining of tumor cells
Urinary bladder – Occludin negative muscle-invasive urothelial carcinoma