Adrenal gland – CA19-9 negative adrenocortical adenoma
Adrenal gland – CA19-9 negative pheochromocytoma
Anal canal – CA19-9 negative squamous cell carcinoma
Breast – CA19-9 negative invasive breast cancer of no special type (NST)
Breast – CA19-9 negative invasive lobular breast cancer
Breast – Invasive breast cancer of no special type (NST) with a moderate to strong CA19-9 positivity of a large subset of tumor cells
Colon – Colorectal adenocarcinoma showing a faint CA19-9 staining at apical membranes of some tumor cells
Colon – Colorectal adenocarcinoma with a weak to moderate CA19-9 staining of tumor cells, mainly at apical membranes
Colon – Colorectal adenocarcinoma with strong CA19-9 staining of tumor cells
Esophagus – Adenocarcinoma with strong CA19-9 immunostaining of tumor cells. Stroma with “contamination artifact”
Esophagus – CA19-9 negative squamous cell carcinoma
Kidney – CA19-9 negative clear cell carcinoma
Kidney – Papillary renal cell carcinoma with weak to moderate CA19-9 positivity of a subset of scattered tumor cells
Liver – CA19-9 negative hepatocellular carcinoma
Liver – Cholangiocellular carcinoma with strong CA19-9 staining of tumor cells
Lung – Adenocarcinoma with strong CA19-9 staining of most tumor cells
Lymph node – CA19-9 negative diffuse large B-cell lymphoma
Lymph node – CA19-9 negative Hodgkin’s lymphoma
Oral cavity – CA19-9 negative squamous cell carcinoma
Ovary – CA19-9 negative clear cell carcinoma
Ovary – CA19-9 negative serous high-grade carcinoma
Ovary – Clear cell carcinoma with strong CA19-9 staining of tumor cells
Ovary – Mucinous carcinoma with strong CA19-9 staining of all cancer cells
Pancreas – CA19-9 negative acinar cell carcinoma
Pancreas – Ductal adenocarcinoma with strong CA19-9 positivity of tumor cells
Pancreas – Ductal adenocarcinoma with strong CA19-9 staining of tumor cells
Pancreas – Neuroendocrine tumor with strong CA19-9 positivity of all tumor cells
Prostate – Adenocarcinoma (Gleason 4+4=8) with a moderate to strong CA19-9 positivity of all tumor cells
Prostate – CA19-9 negative adenocarcinoma (Gleason 3+3=6)
Prostate – CA19-9 negative adenocarcinoma (Gleason 5+5=10)
Salivary gland – Pleomorphic adenoma with strong CA19-9 staining of a small subset of tumor cells
Salivary gland – Warthin tumor with moderate to strong CA19-9 staining of a small subset of tumor cells
Salivary gland – Warthin tumor with strong CA19-9 staining of epithelial tumor cells
Stomach – CA19-9 negative gastrointestinal stromal tumor (GIST)
Stomach – Gastric adenocarcinoma (diffuse type) showing a distinct CA19-9 staining of tumor cells
Stomach – Gastric adenocarcinoma (intestinal type) with Intense CA19-9 staining of all tumor cells. The tumor stroma shows also staining due to a contamination artifact (diffusion of CA 19-9 protein from tumor cells to adjacent structures)
Testis – CA19-9 negative Leydig cell tumor
Testis – CA19-9 negative seminoma
Testis – Embryonal carcinoma with strong CA19-9 staining of tumor cells
Urinary bladder – CA19-9 negative muscle-invasive urothelial carcinoma
Urinary bladder – Muscle-invasive urothelial carcinoma (pT2-4) with strong CA19-9 positivity of tumor cells
Uterus, cervix – Adenocarcinoma with intense CA19-9 staining, predominantly seen at the apical pole of tumor cells
Uterus, cervix – Squamous cell carcinoma with strong CA19-9 staining of all tumor cells
Vagina – Squamous cell carcinoma with strong CA19-9 positivity of cancer cells