Adrenal gland – MX1 negative adrenocortical adenoma
Breast – Invasive breast cancer of no special type (NST) with faint MX1 staining of few tumor cells
Breast – Invasive breast cancer of no special type (NST) with strong MX1 positivity of tumor cells.jpeg
Breast – Invasive lobular breast cancer with moderate to strong MX1 positivity of tumor cells
Breast – MX1 negative invasive lobular breast cancer
Colon – Colorectal adenocarcinoma with strong MX1 immunostaining of tumor cells
Esophagus – Adenocarcinoma with moderate to strong MX1 immunostaining of tumor cells
Esophagus – MX1 negative adenocarcinoma. Strong MX1 staining of inflammatory and endothelial cells
Kidney – MX1 negative clear cell carcinoma
Larynx – Squamous cell carcinoma with strong MX1 immunostaining of tumor cells
Larynx – Squamous cell carcinoma with strong MX1 staining of tumor cells. Stromal and inflammatory cells show a less intense MX1 staining
Liver – Cholangiocellular carcinoma with strong MX1 staining of tumor and stroma cells
Liver – MX1 negative hepatocellular carcinoma
Lung – Adenocarcinoma with strong MX1 staining of tumor cells. Inflammatory and stroma cells are also MX1 positive
Lung – Malignant mesothelioma with strong MX1 positivity of tumor cells
Lymph node – B-CLL with strong MX1 positivity of virtually all tumor cells
Lymph node – Diffuse large B-cell lymphoma with strong MX1 staining of all tumor cells
Lymph node – MX1 negative B-CLL
Lymph node – MX1 negative diffuse large B-cell lymphoma
Lymph node – MX1 negative Hodgkin’s lymphoma. Distinct MX1 staining of non-neoplastic cell types
Lymph node – MX1 negative Hodgkin’s lymphoma. Strong MX1 staining of non-neoplastic cells
Oral cavity – Squamous cell carcinoma with faint MX1 positivity of only few tumor cells. Stromal and inflammatory cells exhibit a markedly more intense MX1 staining
Ovary – MX1 negative serous high-grade carcinoma
Ovary – Serous high-grade carcinoma with strong MX1 staining of all tumor cells
Pancreas – Ductal adenocarcinoma showing strong MX1 staining of tumor cells
Pancreas – MX1 negative neuroendocrine tumor
Penis – Squamous cell carcinoma with strong MX1 staining of tumor cells
Prostate – Adenocarcinoma (Gleason 5+5=10) with strong MX1 immunostaining of tumor cells.jpeg
Prostate – MX1 negative adenocarcinoma (Gleason 3+3=6)
Salivary gland – MX1 negative Warthin tumor. Tumor-associated lymphocytes are MX1 positive
Skin – MX1 negative basal cell carcinoma. Distinct MX1 staining of inflammatory cells
Stomach – Gastric adenocarcinoma (intestinal type) with moderate MX1 immunostaining of tumor cells. Inflammatory and stroma cells are also MX1 positive
Stomach – Gastrointestinal stromal tumor (GIST) with intense MX1 staining of tumor cells
Testis – MX1 negative Leydig cell tumor
Testis – Seminoma with strong MX1 immunostaining of tumor cells. Tumor-infiltrating lymphocytes are also MX1 positive
Testis – Yolk sac tumor with weak MX1 immunostaining of few tumor cells. Strong MX1 staining of inflammatory cells.jpeg
Thyroid – Anaplastic carcinoma with strong MX1 positivity of tumor and stroma cells
Thyroid – MX1 negative medullary carcinoma
Thyroid – Papillary cancer with strong MX1 immunostaining of tumor cells
Urinary bladder – Muscle-invasive urothelial carcinoma with strong MX1 staining of tumor and stroma cells
Urinary bladder – MX1 negative muscle-invasive urothelial carcinoma
Uterus, cervix – Adenocarcinoma with intense MX1 immunostaining of tumor cells
Vulva – Squamous cell carcinoma with strong MX1 staining of tumor cells. Stromal and inflammatory cells show a less intense MX1 staining